FCGR1A Protein (His tag)
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- 抗原 See all FCGR1A 蛋白
- FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This FCGR1A protein is labelled with His tag.
- 原理
- Recombinant Rat FCGR1A/CD64 Protein (His Tag)(Active)
- 序列
- Met 1-Pro 285
- 产品特性
- A DNA sequence encoding the rat FCGR1A (NP_001094306.1) extracellular domain (Met 1-Pro 285) was expressed, fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Rat CD64-his at 10 μg/ml (100 μl/well) can bind biotinylated human IgG1, The EC50 of biotinylated human IgG1 is 0.04-0.08 μg/ml.
- Top Product
- Discover our top product FCGR1A 蛋白
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Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-115) protein (GST tag)
FCGR1A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 25-297) (Active) protein (His tag)FCGR1A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 11-288) (Active) protein (His tag,AVI tag,Biotin)FCGR1A 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 1-374) protein (GST tag)FCGR1A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-292) protein (His tag)Crystallography grade FCGR1A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-374) protein (rho-1D4 tag)Crystallography grade FCGR1A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-281) (Active) protein (His tag)FCGR1A 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-288) (Active) protein (His tag,AVI tag,Biotin)FCGR1A 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
- 别名
- FCGR1A/CD64 (FCGR1A 产品)
- 别名
- CD64 Protein, CD64A Protein, FCRI Protein, IGFR1 Protein, FcgammaRI Protein, Fcgr1 Protein, Fcgr1b Protein, AI323638 Protein, AV092959 Protein, IGGHAFC Protein, FCGR1A Protein, Fc fragment of IgG receptor Ia Protein, Fc receptor, IgG, high affinity I Protein, FCGR1A Protein, Fcgr1a Protein, Fcgr1 Protein
- 背景
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Background: High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membrane glycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of a signal peptide that allows its transport to the surface of a cell, three extracellular immunoglobulin domains of the C2-type that it uses to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.
Synonym: FcgammaRI;Fcgr1;Fcgr1b
- 分子量
- 31.6 kDa
- NCBI登录号
- NP_001094306
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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