FCGR1A Protein (AA 25-297) (His tag)
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- 抗原 See all FCGR1A 蛋白
- FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 25-297
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This FCGR1A protein is labelled with His tag.
- 品牌
- MABSol®
- 序列
- AA 25-297
- 产品特性
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 31.2 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product FCGR1A 蛋白
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Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-115) protein (GST tag)
FCGR1A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 11-288) (Active) protein (His tag,AVI tag,Biotin)FCGR1A 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 1-374) protein (GST tag)FCGR1A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (Active) protein (His tag)FCGR1A 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-292) protein (His tag)Crystallography grade FCGR1A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-374) protein (rho-1D4 tag)Crystallography grade FCGR1A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-281) (Active) protein (His tag)FCGR1A 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A) (AA 16-288) (Active) protein (His tag,AVI tag,Biotin)FCGR1A 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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: "CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels. ..." in: Nature metabolism, Vol. 2, Issue 11, pp. 1284-1304, (2020) (PubMed).
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: "CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels. ..." in: Nature metabolism, Vol. 2, Issue 11, pp. 1284-1304, (2020) (PubMed).
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- 抗原
- FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))
- 别名
- Fc gamma RI / CD64 (FCGR1A 产品)
- 别名
- CD64 Protein, CD64A Protein, FCRI Protein, IGFR1 Protein, FcgammaRI Protein, Fcgr1 Protein, Fcgr1b Protein, AI323638 Protein, AV092959 Protein, IGGHAFC Protein, FCGR1A Protein, Fc fragment of IgG receptor Ia Protein, Fc receptor, IgG, high affinity I Protein, FCGR1A Protein, Fcgr1a Protein, Fcgr1 Protein
- 背景
- Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family. FCGR1A / CD64 contains 3 Ig-like C2-type (immunoglobulin-like) domains. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.
- 分子量
- 32.3 kDa
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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