EPH Receptor B3 Protein (EPHB3) (AA 585-998) (GST tag,His tag)
-
- 抗原 See all EPH Receptor B3 (EPHB3) 蛋白
- EPH Receptor B3 (EPHB3)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 585-998
-
宿主
- 人
-
资源
- Baculovirus infected Insect Cells
- 标记
- This EPH Receptor B3 protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human EphB3/HEK2 Protein (aa 585-998, His & GST Tag)(Active)
- 序列
- Gln 585-Val 998
- 产品特性
- A DNA sequence encoding the human EPHB3 (P54753) (Gln585-Val998) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be 90 nmol/min/mg using Poly(Glu:Tyr) 4:1 as substrate.
- Top Product
- Discover our top product EPHB3 蛋白
-
EPH Receptor B3 (EPHB3) (AA 30-554) protein (His tag)
EPHB3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EPH Receptor B3 (EPHB3) (AA 34-559) protein (His tag)EPHB3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EPH Receptor B3 (EPHB3) (AA 585-998) (Active) protein (His-GST)EPHB3 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
EPH Receptor B3 (EPHB3) (AA 1-998) protein (GST tag)EPHB3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor B3 (EPHB3) (AA 899-997) protein (GST tag)EPHB3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor B3 (EPHB3) (Active) protein (His tag)EPHB3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE Active
-
- 限制
- 仅限研究用
-
- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- 抗原
- EPH Receptor B3 (EPHB3)
- 别名
- EphB3/HEK2 (EPHB3 产品)
- 别名
- tck Protein, MGC83457 Protein, EPHB3 Protein, ETK2 Protein, HEK2 Protein, TYRO6 Protein, AW456895 Protein, Cek10 Protein, Etk2 Protein, MDK5 Protein, Sek4 Protein, Tyro6 Protein, CEK10 Protein, EK10 Protein, ek3 Protein, ephb3 Protein, fc62d03 Protein, rtk3 Protein, wu:fc62d03 Protein, zek3 Protein, EPH receptor B3 Protein, EPH receptor B3 L homeolog Protein, Eph receptor B3 Protein, eph receptor B3a Protein, Eph receptor tyrosine kinase Protein, EPHB3 Protein, ephb3.L Protein, ephb3 Protein, Ephb3 Protein, ephb3a Protein
- 背景
-
Background: Ephrin type-B receptor 3, also known as EphB3 or HEK2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. Ephrin receptors are components of cell signalling pathways involved in animal growth and development, forming the largest sub-family of receptor tyrosine kinases (RTKs). Ligand-mediated activation of Ephs induce various important downstream effects and Eph receptors have been studied for their potential roles in the development of cancer. EphB receptor tyrosine kinases are enriched at synapses, suggesting that these receptors play a role in synapse formation or function. We find that EphrinB binding to EphB induces a direct interaction of EphB with NMDA-type glutamate receptors. This interaction occurs at the cell surface and is mediated by the extracellular regions of the two receptors, but does not require the kinase activity of EphB.
Synonym: ETK2,HEK2,TYRO6
- 分子量
- 74.7 kDa
- UniProt
- P54753
- 途径
- RTK signaling
-
