EPH Receptor B2 Protein (EPHB2) (AA 570-987) (GST tag,His tag)
-
- 抗原 See all EPH Receptor B2 (EPHB2) 蛋白
- EPH Receptor B2 (EPHB2)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 570-987
-
宿主
- 人
-
资源
- Baculovirus infected Insect Cells
- 标记
- This EPH Receptor B2 protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human EphB2 Protein (aa 570-987, His &GST Tag)(Active)
- 序列
- Gly570-Val987
- 产品特性
- A DNA sequence encoding the human EPHB2 (P29323-3) (Gly570-Val987) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be 120 nmol/min/mg using Poly(Glu:Tyr) 4:1 as substrate.
- Top Product
- Discover our top product EPHB2 蛋白
-
EPH Receptor B2 (EPHB2) (AA 19-543) protein (His tag)
EPHB2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EPH Receptor B2 (EPHB2) (AA 19-542) protein (His tag)EPHB2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EPH Receptor B2 (EPHB2) (AA 19-543) protein (His tag)EPHB2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EPH Receptor B2 (EPHB2) (AA 570-987) (Active) protein (His-GST)EPHB2 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
EPH Receptor B2 (EPHB2) (AA 226-325) protein (GST tag)EPHB2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor B2 (EPHB2) (AA 565-986) protein (His tag)Crystallography grade EPHB2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
EPH Receptor B2 (EPHB2) (AA 19-543) protein (His tag)Crystallography grade EPHB2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
EPH Receptor B2 (EPHB2) (AA 565-1055) protein (His tag)Crystallography grade EPHB2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
EPH Receptor B2 (EPHB2) (AA 19-543) protein (His tag)Crystallography grade EPHB2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
EPH Receptor B2 (EPHB2) (AA 19-986) protein (rho-1D4 tag)Crystallography grade EPHB2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 3 mM DTT, 10 % glycerol
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- 抗原
- EPH Receptor B2 (EPHB2)
- 别名
- EphB2 (EPHB2 产品)
- 别名
- CAPB Protein, DRT Protein, EK5 Protein, EPHT3 Protein, ERK Protein, Hek5 Protein, PCBC Protein, Tyro5 Protein, ERK2 Protein, ERT1 Protein, MAPK2 Protein, P42MAPK Protein, PRKM1 Protein, PRKM2 Protein, p38 Protein, p40 Protein, p41 Protein, p41mapk Protein, RGD1564232 Protein, Cek5 Protein, Drt Protein, ETECK Protein, Erk Protein, Nuk Protein, Prkm5 Protein, Qek5 Protein, Sek3 Protein, cek5 Protein, ephb2 Protein, xEphB2 Protein, si:ch73-160e9.1 Protein, tpx2 Protein, wu:fb09e10 Protein, wu:fc64a03 Protein, wu:fi18g12 Protein, zgc:112296 Protein, EPH receptor B2 Protein, mitogen-activated protein kinase 1 Protein, Eph receptor B2 Protein, EPH receptor B2 L homeolog Protein, eph receptor B2a Protein, eph receptor B2b Protein, EPHB2 Protein, MAPK1 Protein, Ephb2 Protein, ephb2.L Protein, ephb2a Protein, ephb2b Protein
- 背景
-
Background: Ephrin type-B receptor 2, also known as EphB2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. EphB2 receptor tyrosine kinase phosphorylates syndecan-2 and that this phosphorylation event is crucial for syndecan-2 clustering and spine formation. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. Ephrin receptors are components of cell signalling pathways involved in animal growth and development, forming the largest sub-family of receptor tyrosine kinases (RTKs). Ligand-mediated activation of Ephs induce various important downstream effects and Eph receptors have been studied for their potential roles in the development of cancer. EphB receptor tyrosine kinases are enriched at synapses, suggesting that these receptors play a role in synapse formation or function. We find that EphrinB binding to EphB induces a direct interaction of EphB with NMDA-type glutamate receptors. This interaction occurs at the cell surface and is mediated by the extracellular regions of the two receptors, but does not require the kinase activity of EphB.
Synonym: CAPB,DRT,EK5,EPHT3,ERK,Hek5,PCBC,Tyro5,EPHB2,Ephrin type-B receptor 2
- 分子量
- 75.2 kDa
- 途径
- RTK signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
-
