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EPH Receptor A6 Protein (Epha6) (Fc Tag)

Epha6 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
产品编号 ABIN7195532
发货至: 中国
  • 抗原 See all EPH Receptor A6 (Epha6) 蛋白
    EPH Receptor A6 (Epha6)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 8
    • 5
    • 2
    小鼠
    资源
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This EPH Receptor A6 protein is labelled with Fc Tag.
    原理
    Recombinant Mouse EphA6/EHK-2 Protein (Fc Tag)(Active)
    序列
    Met 1-Gln 546
    产品特性
    A DNA sequence encoding the extracellular domain of mouse EphA6 (NP_031964.2) (Met 1-Gln 546) was fused with the Fc region of human IgG1 at the C-terminus.
    纯度
    > 90 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA. Immobilized mouse EphrinA3 at 1 μg/ml (100 μl/well) can bind mouse EPHA6 / chimera with a linear ranger of 6.25-400 ng/ml.
    Top Product
    Discover our top product Epha6 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    EPH Receptor A6 (Epha6)
    别名
    EphA6/EHK-2 (Epha6 产品)
    别名
    EPHA6 Protein, Ehk2 Protein, Hek12 Protein, m-ehk2 Protein, EHK-2 Protein, EHK2 Protein, EK12 Protein, EPA6 Protein, HEK12 Protein, PRO57066 Protein, EPH receptor A6 Protein, Eph receptor A6 Protein, EPHA6 Protein, epha6 Protein, Epha6 Protein
    背景

    Background: Ephrin type-A receptor 6, also known as EphA6 or EHK2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. Eph receptor−mediated signaling, which is triggered by ephrins7, probably modifies the properties of synapses during synaptic activation and remodeling. Ephrin receptors are components of cell signalling pathways involved in animal growth and development, forming the largest sub-family of receptor tyrosine kinases (RTKs). Ligand-mediated activation of Ephs induce various important downstream effects and Eph receptors have been studied for their potential roles in the development of cancer. In the vomeronasal system, Ephrin-A5/EphA6 interactions mediate attraction or adhesion rather than repulsion.

    Synonym: Ehk2;Hek12;m-ehk2

    分子量
    85 kDa
    NCBI登录号
    NP_031964
    途径
    RTK signaling
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