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EPH Receptor A3 Protein (EPHA3) (Fc Tag)

EPHA3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
产品编号 ABIN7195519
发货至: 中国
  • 抗原 See all EPH Receptor A3 (EPHA3) 蛋白
    EPH Receptor A3 (EPHA3)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 17
    • 6
    • 3
    • 1
    小鼠
    资源
    • 12
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This EPH Receptor A3 protein is labelled with Fc Tag.
    原理
    Recombinant Mouse EphA3 Protein (Fc Tag)(Active)
    序列
    Met1-His541
    产品特性
    A DNA sequence encoding the extracellular domain of mouse EPHA3 (NP_034270.1)(Met1-His541) was expressed with the Fc region of human IgG1 at the C-terminus.
    纯度
    > 90 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Biological Activity Comment
    Measured by its binding ability in a functional ELISA.Immobilized mouse EFNA5-His at 10 μg/ml (100 μl/well) can bind mouse EPHA3-Fc, The EC50 of rat mouse EPHA3-Fc is 12.3-28.9 ng/ml.
    Top Product
    Discover our top product EPHA3 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    EPH Receptor A3 (EPHA3)
    别名
    EphA3 (EPHA3 产品)
    别名
    EK4 Protein, ETK Protein, ETK1 Protein, HEK Protein, HEK4 Protein, TYRO4 Protein, EPHA3 Protein, AW492086 Protein, Cek4 Protein, End3 Protein, Hek Protein, Hek4 Protein, Mek4 Protein, Tyro4 Protein, CEK4 Protein, EPH receptor A3 Protein, ephrin type-A receptor 3 Protein, Eph receptor A3 Protein, EPHA3 Protein, LOC100439679 Protein, Epha3 Protein
    背景

    Background: EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

    Synonym: AW492086;Cek4;End3;ETK1;Hek;Hek4;Mek4;Tyro4

    分子量
    85.7 kDa
    NCBI登录号
    NP_034270
    途径
    RTK signaling, Regulation of Cell Size
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