ECE1 Protein (His tag)
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- 抗原 See all ECE1 蛋白
- ECE1 (Endothelin-Converting Enzyme 1 (ECE1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This ECE1 protein is labelled with His tag.
- 原理
- Recombinant Human ECE1 Protein (His Tag)
- 序列
- Gln90-Trp770
- 产品特性
- Recombinant Human Endothelin-converting Enzyme 1 is produced by our Mammalian expression system and the target gene encoding Gln90-Trp770 is expressed with a 8His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product ECE1 蛋白
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Endothelin-Converting Enzyme 1 (ECE1) (AA 1-770) protein (GST tag)
ECE1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Endothelin-Converting Enzyme 1 (ECE1) (AA 1-770) protein (Strep Tag)Crystallography grade ECE1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Endothelin-Converting Enzyme 1 (ECE1) (AA 1-769) protein (Strep Tag)Crystallography grade ECE1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Endothelin-Converting Enzyme 1 (ECE1) (AA 90-770) protein (His tag)Crystallography grade ECE1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelin-Converting Enzyme 1 (ECE1) (AA 89-769) protein (His tag)Crystallography grade ECE1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Endothelin-Converting Enzyme 1 (ECE1) proteinECE1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ECE1 (Endothelin-Converting Enzyme 1 (ECE1))
- 别名
- ECE1 (ECE1 产品)
- 别名
- ECE Protein, Ece Protein, AW322500 Protein, ECE-1 Protein, ECE-1a Protein, ECE-1b Protein, ECE-1d Protein, ece1 Protein, MGC52874 Protein, MGC130791 Protein, fd11b07 Protein, wu:fd11b07 Protein, zgc:154079 Protein, endothelin converting enzyme 1 Protein, endothelin converting enzyme like 1 Protein, endothelin converting enzyme 1 L homeolog Protein, endothelin-converting enzyme 1 Protein, Endothelin-converting enzyme 1 Protein, ECE1 Protein, ECEL1 Protein, Ece1 Protein, ece1.L Protein, Za10_0551 Protein, Arch_0474 Protein, Closa_0961 Protein, Odosp_0578 Protein, Bacsa_1787 Protein, Weevi_2017 Protein, Fluta_3444 Protein, Sphch_2390 Protein, ece1 Protein
- 背景
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Background: Endothelin-Converting Enzyme-1 (ECE-1) is a single-pass type I I transmembrane (TM) protein with a short cytoplasmic tail and a large ectodomain. ECE-1 is a zinc protease of the neprilysin (NEP) family, which also includes ECE-2, PEX, XCE, DINE, and Kell, and several NEP-like proteins. It is widely expressed and has several alternatively spliced forms that differ in their TM domain or cytoplasmic tail. All isoforms of ECE-1 are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Endothelin-converting enzyme-1 is involved in the proteolytic processing of Endothelin-1 (EDN1), Endothelin-2 (EDN2), and Endothelin-3 (EDN3) to biologically active peptides. Defects in ECE1 are a cause of Hirschsprung disease, cardiac defects and autonomic dysfunction (HSCRCDAD). It is a form of Hirschsprung disease with skip-lesions defects, craniofacial abnormalities and other dysmorphic features, and autonomic dysfunction.
Synonym: Endothelin-converting enzyme 1, ECE-1
- 分子量
- 78.8 kDa
- UniProt
- P42892
- 途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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