ESM1 Protein (His tag)
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- 抗原 See all ESM1 蛋白
- ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This ESM1 protein is labelled with His tag.
- 原理
- Recombinant Human ESM1/Endocan Protein (His Tag)(Active)
- 序列
- Met 1-Arg184
- 产品特性
- A DNA sequence encoding the human ESM1 (NP_008967.1) (Met1-Arg184) was expressed with a C-terminal polyhistidine tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of Jurkat human acute T cell leukemia cells.When 8 x 104 cells/well are added to ESM1-His coated plates (10μg/mL, 100 μL/well), approximately 48% will adhere after 30 minutes at 37°C.
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- Discover our top product ESM1 蛋白
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Endothelial Cell-Specific Molecule 1 (ESM1) protein (His tag)
ESM1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 1-184) protein (GST tag)ESM1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 85-184) protein (GST tag)ESM1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Endothelial Cell-Specific Molecule 1 (ESM1) protein (His tag)ESM1 宿主: 人 宿主: 人细胞 Recombinant >90 % as determined by reducing SDS-PAGE.
Endothelial Cell-Specific Molecule 1 (ESM1) protein (His tag)ESM1 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 20-184) protein (His tag)Crystallography grade ESM1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 22-184) protein (His tag)Crystallography grade ESM1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))
- 别名
- ESM1/Endocan (ESM1 产品)
- 别名
- ESM1 Protein, zgc:153027 Protein, 0610042H23Rik Protein, AV004503 Protein, ESM-1 Protein, Pg25 Protein, endocan Protein, endothelial cell specific molecule 1 Protein, endothelial cell-specific molecule 1 Protein, ESM1 Protein, esm1 Protein, Esm1 Protein
- 背景
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Background: ESM1 is a secreted protein which is produced by adipocytes. It has been noticed that ESM1 may play some role in obesity-associated vascular disease since circulating ESM-1 levels are reduced in the overweight and obese. ESM1 is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of ESM1 gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. Recently, ESM1 has been described as a specific biomarker of tip cells during neoangiogenesis. Its expression has been shown to be increase in presence of pro-angiogenic growth factors such as VEGF or FGF-2. In hypervascularized cancers, overexpression of endocan has been detected by immunohistochemistry using monoclonal antibodies against ESM1.
Synonym: endocan
- 分子量
- 19.6 kDa
- NCBI登录号
- NP_008967
- 途径
- Growth Factor Binding
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