电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

ESM1 Protein (His tag)

ESM1 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7195501
发货至: 中国
  • 抗原 See all ESM1 蛋白
    ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))
    蛋白类型
    Recombinant
    宿主
    • 10
    • 6
    • 3
    小鼠
    资源
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Baculovirus infected Insect Cells
    标记
    This ESM1 protein is labelled with His tag.
    原理
    Recombinant Mouse ESM1/Endocan Protein (Baculovirus, His Tag)
    序列
    Met1-Arg184
    产品特性
    A DNA sequence encoding the mouse TLR2 (Q9QYY7) (Met1-Arg184) was fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product ESM1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))
    别名
    ESM1/Endocan (ESM1 产品)
    别名
    ESM1 Protein, zgc:153027 Protein, 0610042H23Rik Protein, AV004503 Protein, ESM-1 Protein, Pg25 Protein, endocan Protein, endothelial cell specific molecule 1 Protein, endothelial cell-specific molecule 1 Protein, ESM1 Protein, esm1 Protein, Esm1 Protein
    背景

    Background: ESM1 is a secreted protein which is produced by adipocytes. It has been noticed that ESM1 may play some role in obesity-associated vascular disease since circulating ESM-1 levels are reduced in the overweight and obese. ESM1 is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of ESM1 gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. Recently, ESM1 has been described as a specific biomarker of tip cells during neoangiogenesis. Its expression has been shown to be increase in presence of pro-angiogenic growth factors such as VEGF or FGF-2. In hypervascularized cancers, overexpression of endocan has been detected by immunohistochemistry using monoclonal antibodies against ESM1.

    Synonym: Endothelial cell-specific molecule 1, ESM-1, Esm1, Endocan

    分子量
    19.1 kDa
    UniProt
    Q9QYY7
    途径
    Growth Factor Binding
You are here: