Ectodysplasin A2 Receptor Protein (EDA2R) (His tag)
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- 抗原 See all Ectodysplasin A2 Receptor (EDA2R) 蛋白
- Ectodysplasin A2 Receptor (EDA2R)
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 人细胞
- 标记
- This Ectodysplasin A2 Receptor protein is labelled with His tag.
- 原理
- Recombinant Mouse XEDAR/EDA2R Protein (His Tag)
- 序列
- Met1-Thr138
- 产品特性
- Recombinant Mouse Ectodysplasin A2 Receptor is produced by our Mammalian expression system and the target gene encoding Met1-Thr138 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product EDA2R 蛋白
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Ectodysplasin A2 Receptor (EDA2R) (AA 1-138) protein (Fc Tag)
EDA2R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Ectodysplasin A2 Receptor (EDA2R) (AA 1-138) protein (Fc Tag)EDA2R 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Ectodysplasin A2 Receptor (EDA2R) (AA 1-297) protein (GST tag)EDA2R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ectodysplasin A2 Receptor (EDA2R) (AA 1-110) protein (GST tag)EDA2R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ectodysplasin A2 Receptor (EDA2R) protein (His tag)EDA2R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Ectodysplasin A2 Receptor (EDA2R) protein (Fc Tag)EDA2R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE
Ectodysplasin A2 Receptor (EDA2R) (AA 1-297) protein (Strep Tag)Crystallography grade EDA2R 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Ectodysplasin A2 Receptor (EDA2R) (AA 1-297) protein (Strep Tag)Crystallography grade EDA2R 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Ectodysplasin A2 Receptor (EDA2R) (AA 1-138) protein (His tag)Crystallography grade EDA2R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Ectodysplasin A2 Receptor (EDA2R) (AA 160-297) protein (His tag)Crystallography grade EDA2R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Ectodysplasin A2 Receptor (EDA2R)
- 别名
- XEDAR/EDA2R (EDA2R 产品)
- 别名
- EDA-A2R Protein, EDAA2R Protein, TNFRSF27 Protein, XEDAR Protein, 9430060M22Rik Protein, Xedar Protein, RGD1564025 Protein, ectodysplasin A2 receptor Protein, EDA2R Protein, Eda2r Protein
- 背景
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Background: Tumor necrosis factor receptor superfamily member 27, also known as XEDAR and EDA2R, is a type III transmembrane protein of the TNFR superfamily. EDA2R consists of extracellular domain (ECD) with 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. EDA2R is widely expressed, notably in embryonic basal epidermal cells and maturing hair follicles. Even though it does not contain a cytoplasmic death domain, EDA2R can associate with Fas and induce EDA-A2 dependent apoptosis. Its transcription is directly induced by p53, and it mediated cell death is p53 dependent. it is down-regulated in breast, colon, and lung cancers, particularly in cases with p53 mutations. It also plays a role in EDA-A2 induced skeletal muscle degeneration and osteoblast differentiation. Mutations in the EDA gene are associated with the X-linked form of Hypohidrotic Ectodermal Dysplasia (HED), a disease typically characterized by abnormal hair, teeth and sweat glands.
Synonym: Ectodysplasin A2 receptor, EDA-A2 receptor, EDA-A2R, Tumor necrosis factor receptor superfamily member XEDAR, Tumor necrosis factor receptor superfamily member 27, X-linked ectodysplasin-A2 receptor,EDAA2R, TNFRSF27, XEDAR,EDAR2
- 分子量
- 16.4 kDa
- UniProt
- Q8BX35
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