Ectodysplasin A2 Receptor Protein (EDA2R) (Fc Tag)
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- 抗原 See all Ectodysplasin A2 Receptor (EDA2R) 蛋白
- Ectodysplasin A2 Receptor (EDA2R)
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This Ectodysplasin A2 Receptor protein is labelled with Fc Tag.
- 原理
- Recombinant Rat XEDAR/EDA2R Protein (Fc Tag)
- 序列
- Met2-Glu137
- 产品特性
- A DNA sequence encoding the rat EDA2R (D3ZAX4) (Met2-Glu137) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 94 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product EDA2R 蛋白
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Ectodysplasin A2 Receptor (EDA2R) (AA 1-138) protein (Fc Tag)
EDA2R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Ectodysplasin A2 Receptor (EDA2R) (AA 1-138) protein (Fc Tag)EDA2R 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Ectodysplasin A2 Receptor (EDA2R) protein (His tag)EDA2R 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Ectodysplasin A2 Receptor (EDA2R) (AA 1-297) protein (GST tag)EDA2R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ectodysplasin A2 Receptor (EDA2R) (AA 1-110) protein (GST tag)EDA2R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ectodysplasin A2 Receptor (EDA2R) protein (His tag)EDA2R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Ectodysplasin A2 Receptor (EDA2R) (AA 1-297) protein (Strep Tag)Crystallography grade EDA2R 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Ectodysplasin A2 Receptor (EDA2R) (AA 1-297) protein (Strep Tag)Crystallography grade EDA2R 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Ectodysplasin A2 Receptor (EDA2R) (AA 1-138) protein (His tag)Crystallography grade EDA2R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Ectodysplasin A2 Receptor (EDA2R) (AA 160-297) protein (His tag)Crystallography grade EDA2R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Ectodysplasin A2 Receptor (EDA2R)
- 别名
- XEDAR/EDA2R (EDA2R 产品)
- 别名
- EDA-A2R Protein, EDAA2R Protein, TNFRSF27 Protein, XEDAR Protein, 9430060M22Rik Protein, Xedar Protein, RGD1564025 Protein, ectodysplasin A2 receptor Protein, EDA2R Protein, Eda2r Protein
- 背景
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Background: Tumor necrosis factor receptor superfamily member 27, also known as X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, XEDAR and TNFRSF27, is a single-pass type I II membrane protein. TNFRSF27 / EDA2R contains three TNFR-Cys repeats. It is a new member of the tumor necrosis factor receptor family that has been shown to be highly expressed in ectodermal derivatives during embryonic development and binds to ectodysplasin-A2 (EDA-A2). TNFRSF27 / EDA2R is a receptor for EDA isoform A2, but not for EDA isoform A1. TNFRSF27 / EDA2R mediates the activation of the NF-kappa-B and JNK pathways. The activation seems to be mediated by binding to TRAF3 and TRAF6. Ectodysplasin, a member of the tumor necrosis factor family, is encoded by the anhidrotic ectodermal dysplasia EDA gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that differ only by an insertion of two amino acids. This insertion functions to determine receptor binding specificity, such that EDA-A1 binds only the receptor EDAR, whereas EDA-A2 binds only the related, but distinct, X-linked ectodysplasin-A2 receptor (XEDAR).
Synonym: EDA2R
- 分子量
- 42.3 kDa
- UniProt
- D3ZAX4
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