DCLK1 Protein (AA 1-705) (GST tag,His tag)
-
- 抗原 See all DCLK1 蛋白
- DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 1-705
-
宿主
- 人
-
资源
- Baculovirus infected Insect Cells
- 标记
- This DCLK1 protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human DCAMKL1 Protein (aa 1-705, His & GST Tag)(Active)
- 序列
- Met 1-Val 705
- 产品特性
- A DNA sequence encoding the human DCLK1 (O15075-1) (Met 1-Val 705) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 84 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be 6.1 nmol/min/mg using synthetic Autocamtide-2 peptide (KKALRRQETVDAL-amide) as substrate.
- Top Product
- Discover our top product DCLK1 蛋白
-
Doublecortin-Like Kinase 1 (DCLK1) (AA 1-729) (Active) protein (GST tag)
DCLK1 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Doublecortin-Like Kinase 1 (DCLK1) (AA 586-740) protein (His-IF2DI Tag)DCLK1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Doublecortin-Like Kinase 1 (DCLK1) (AA 640-729) protein (GST tag)DCLK1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Doublecortin-Like Kinase 1 (DCLK1) (AA 1-740) protein (Strep Tag)Crystallography grade DCLK1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Doublecortin-Like Kinase 1 (DCLK1) (AA 1-756) protein (Strep Tag)Crystallography grade DCLK1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Doublecortin-Like Kinase 1 (DCLK1) (AA 1-754), (full length) protein (His-SUMO Tag)DCLK1 宿主: Giardia lamblia 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
-
- 限制
- 仅限研究用
-
- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol, 0.5 mM PMSF
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- 抗原
- DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
- 别名
- DCAMKL1 (DCLK1 产品)
- 别名
- DCLK1 Protein, DCAMKL1 Protein, dcamkl1 Protein, dclk1 Protein, wu:fc51f11 Protein, zgc:153709 Protein, MGC145348 Protein, CL1 Protein, CLICK1 Protein, DCDC3A Protein, DCLK Protein, 1700113D08Rik Protein, 2810480F11Rik Protein, AI836758 Protein, Click-I Protein, Cpg16 Protein, Dcamkl1 Protein, Dcl Protein, Dclk Protein, mKIAA0369 Protein, Ania4 Protein, doublecortin like kinase 1 Protein, doublecortin-like kinase 1a Protein, serine/threonine-protein kinase DCLK1 Protein, doublecortin-like kinase 2 Protein, doublecortin-like kinase 1 Protein, DCLK1 Protein, dclk1a Protein, LOC587664 Protein, dclk2 Protein, LOC100539645 Protein, Dclk1 Protein
- 背景
-
Background: DCAMKL1, also known as DCLK1, is a member of the protein kinase superfamily and the doublecortin family. It contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. Its microtubule-polymerizing activity is independent of its protein kinase activity. DCAMKL1 may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. It may also participate in functions of the mature nervous system.
Synonym: CL1,CLICK1,DCAMKL1,DCDC3A,DCLK
- 分子量
- 106 kDa
-
