DDC Protein (His tag)
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- 抗原 See all DDC 蛋白
- DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- Baculovirus infected Insect Cells
- 标记
- This DDC protein is labelled with His tag.
- 原理
- Recombinant Mouse DOPA Decarboxylase/DDC Protein (His Tag)
- 序列
- Met 1-Glu 480
- 产品特性
- A DNA sequence encoding the mouse DDC (O88533) (Met 1-Glu 480) was expressed,with a C-terminal polyhistidine tag.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product DDC 蛋白
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Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 1-480) protein (His tag)
DDC 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 296-401) protein (His-IF2DI Tag)DDC 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 1-480) protein (GST tag)DDC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (AA 371-480) protein (GST tag)DDC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (Active) protein (His tag)DDC 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)DDC 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 20 % glycerol, 3 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
- 别名
- DOPA Decarboxylase/DDC (DDC 产品)
- 别名
- AADC Protein, wu:fa56d05 Protein, wu:fd59h03 Protein, wu:fk20h01 Protein, zgc:65801 Protein, zgc:76929 Protein, Ddc Protein, DdcDv Protein, Dvir\\GJ17995 Protein, GJ17995 Protein, dvir_GLEANR_2561 Protein, Aadc Protein, 5-HT Protein, CG10697 Protein, DDC Protein, DdcDm Protein, Dmel\\CG10697 Protein, ddc Protein, fDDC Protein, l(2)37Bl Protein, l(2)37Ch Protein, l(2)k02104 Protein, dopa decarboxylase Protein, Dopa-decarboxylase Protein, dopa decarboxylase (aromatic L-amino acid decarboxylase) Protein, Dopa decarboxylase Protein, dopa decarboxylase L homeolog Protein, DDC Protein, ddc Protein, Ddc Protein, Dvir\Ddc Protein, ddc.L Protein
- 背景
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Background: Dopa Decarboxylase (DDC), also known as AADC and Aromatic-L-amino acid decarboxylase, is a 54 kDa member of the group II decarboxylase family of proteins.It is a vitamin B6-dependent homodimeric enzyme that catalyzes the decarboxylation of both L-3,4-dihydroxyphenylalanine (L-DOPA) and L-5-hydroxytryptophan to dopamine and serotonin, respectively, which are major mammalian neurotransmitters and hormones belonging to catecholamines and indoleamines. Since L-DOPA is regularly used to treat the symptoms of Parkinson's disease, the catalytic pathway is of particular research interest. Defects of DDC are associated with severe developmental delay, oculogyric crises (OGC), as well as autosomal recessive disorder AADC deficiency, an early onset inborn error in neurotransmitter metabolism which can lead to catecholamine and serotonin deficiency.
Synonym: Aadc
- 分子量
- 55.2 kDa
- UniProt
- O88533
- 途径
- Dopaminergic Neurogenesis
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