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DMP1 Protein (His tag)

DMTF1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318398
发货至: 中国
  • 抗原 See all DMP1 (DMTF1) 蛋白
    DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 2
    资源
    • 2
    • 2
    • 2
    • 2
    • 1
    人细胞
    标记
    This DMP1 protein is labelled with His tag.
    原理
    Recombinant Human DMP1 Protein (His Tag)
    序列
    Lys17-Tyr513
    产品特性
    Recombinant Human Dentin matrix protein 1 is produced by our Mammalian expression system and the target gene encoding Lys17-Tyr513 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DMTF1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
    别名
    DMP1 (DMTF1 产品)
    别名
    DMP1 Protein, DMTF Protein, hDMP1 Protein, Dimp Protein, Dmp1 Protein, DMTF1 Protein, zgc:92448 Protein, cyclin D binding myb like transcription factor 1 Protein, cyclin D binding myb-like transcription factor 1 Protein, DMTF1 Protein, Dmtf1 Protein, dmtf1 Protein
    背景

    Background: Dentin Matrix Acidic Phosphoprotein 1 (DMP-1) is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. DMP-1 is expressed in teeth particularly in odontoblast, ameloblast, and cementoblast. DMP-1 is critical for proper mineralization of bone and dentin. DMP-1 may have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, the unphosphorylated form of DMP-1 acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase, DMP-1 is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite. DMP-1 mutations have also been shown to cause rickets hypophosphatemic autosomal recessive type 1 (ARHR1).

    Synonym: Dentin Matrix Acidic Phosphoprotein 1, DMP-1, Dentin Matrix Protein 1, DMP1,ARHP,ARHR

    分子量
    55.0 kDa
    UniProt
    Q13316
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