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CRNN Protein (His tag)

CRNN 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318337
发货至: 中国
  • 抗原 See all CRNN 蛋白
    CRNN (Cornulin (CRNN))
    蛋白类型
    Recombinant
    宿主
    资源
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This CRNN protein is labelled with His tag.
    原理
    Recombinant Human Cornulin/CRNN Protein (His Tag)
    序列
    Met 1-Ser140
    产品特性
    Recombinant Human Cornulin is produced by our E.coli expression system and the target gene encoding Met1-Ser140 is expressed with a 6His tag at the N-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CRNN 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CRNN (Cornulin (CRNN))
    别名
    Cornulin/CRNN (CRNN 产品)
    别名
    C1orf10 Protein, DRC1 Protein, PDRC1 Protein, SEP53 Protein, RGD1311778 Protein, Gm1015 Protein, cornulin Protein, CRNN Protein, Crnn Protein, LOC100359146 Protein
    背景

    Background: Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When Cornulin is overexpressed in oral squamous carcinoma cell lines, it regulates negatively cell proliferation by the induction of G1 arrest.

    Synonym: Cornulin, 53 kDa Putative Calcium-Binding Protein, 53 kDa Squamous Epithelial-Induced Stress Protein, 58 kDa Heat Shock Protein, Squamous Epithelial Heat Shock Protein 53, Tumor-Related Protein, CRNN, C1orf10, DRC1, PDRC1, SEP53

    分子量
    17.5 kDa
    UniProt
    Q9UBG3
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