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CRNN Protein (AA 1-140) (His tag)

CRNN 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096431
发货至: 中国
  • 抗原 See all CRNN 蛋白
    CRNN (Cornulin (CRNN))
    蛋白类型
    Recombinant
    产品特性
    AA 1-140
    宿主
    资源
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This CRNN protein is labelled with His tag.
    原理
    Recombinant Human Cornulin (N-6His)
    序列
    MGSSHHHHHH SSGLVPRGSH MPQLLQNING IIEAFRRYAR TEGNCTALTR GELKRLLEQE FADVIVKPHD PATVDEVLRL LDEDHTGTVE FKEFLVLVFK VAQACFKTLS ESAEGACGSQ ESGSLHSGAS QELGEGQRSG TEVGRAGKGQ HYEGSSHRQS
    产品特性
    Recombinant Human Cornulin is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser140) of Human Cornulin fused with a His tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CRNN 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    CRNN (Cornulin (CRNN))
    别名
    cornulin (CRNN 产品)
    别名
    C1orf10 Protein, DRC1 Protein, PDRC1 Protein, SEP53 Protein, RGD1311778 Protein, Gm1015 Protein, cornulin Protein, CRNN Protein, Crnn Protein, LOC100359146 Protein
    Sub Type
    Fusionprotein
    背景
    Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When Cornulin is overexpressed in oral squamous carcinoma cell lines, it regulates negatively cell proliferation by the induction of G1 arrest.
    Alternative Names: Cornulin, 53 kDa Putative Calcium-Binding Protein, 53 kDa Squamous Epithelial-Induced Stress Protein, 58 kDa Heat Shock Protein, Squamous Epithelial Heat Shock Protein 53, Tumor-Related Protein, CRNN, C1orf10, DRC1, PDRC1, SEP53
    分子量
    17.45 kDa
    UniProt
    Q9UBG3
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