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Complement Factor B Protein (CFB) (His tag)

CFB 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318328
发货至: 中国
  • 抗原 See all Complement Factor B (CFB) 蛋白
    Complement Factor B (CFB)
    蛋白类型
    Recombinant
    宿主
    • 12
    • 6
    • 4
    • 1
    资源
    • 14
    • 6
    • 2
    • 1
    人细胞
    标记
    This Complement Factor B protein is labelled with His tag.
    原理
    Recombinant Human Complement Factor B/CFB Protein (His Tag)
    序列
    Thr 26-Leu764
    产品特性
    Recombinant Human Complement Factor B is produced by our Mammalian expression system and the target gene encoding Thr26-Leu764 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CFB 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    Complement Factor B (CFB)
    别名
    Complement Factor B/CFB (CFB 产品)
    别名
    AHUS4 Protein, BF Protein, BFD Protein, CFAB Protein, FB Protein, FBI12 Protein, GBG Protein, H2-Bf Protein, PBF2 Protein, bf Protein, Bf-1 Protein, Brre-Bf Protein, zgc:114032 Protein, Bf Protein, Sp152 Protein, bfb-A Protein, Bf B Protein, LOC397725 Protein, bf/c2 Protein, CFB Protein, AI195813 Protein, AI255840 Protein, B Protein, C2 Protein, Fb Protein, Da1-24 Protein, complement factor B Protein, complement factor B S homeolog Protein, complement factor B L homeolog Protein, CFB Protein, cfb Protein, bf Protein, cfb.S Protein, cfb.L Protein, bf/c2 Protein, LOC100555981 Protein, Cfb Protein
    背景

    Background: Complement Factor B (CFB) belongs to the peptidase S1 family of enzymes. It is expressed by hepatocytes and macrophages and localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. CFB which is a component of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.

    Synonym: Complement Factor B, C3/C5 Convertase, Glycine-Rich Beta Glycoprotein, GBG, PBF2, Properdin Factor B, CFB, BF, BFD

    分子量
    84.1 kDa
    UniProt
    P00751
    途径
    Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
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