C1QB Protein (His tag)
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- 抗原 See all C1QB 蛋白
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This C1QB protein is labelled with His tag.
- 原理
- Recombinant Human C1QB/C1qB Protein (His Tag)
- 序列
- Met 1-Ala 253
- 产品特性
- A DNA sequence encoding the human C1QB (NP_000482.3) precursor (Met 1-Ala 253) was expressed, with a carboxy-terminal polyhistidine tag.
- 纯度
- > 94 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product C1QB 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, 0.5 mM TCEP, 10 % glycerol, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
- 别名
- C1QB/C1qB (C1QB 产品)
- 别名
- complement C1q B chain Protein, complement component 1, q subcomponent, beta polypeptide Protein, C1QB Protein, C1qb Protein
- 背景
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Background: Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Southern blot analysis of chromosomal DNA from vertebrate species demonstrated highest similarity between the C1qB genes, followed by C1qC and finally C1qA. Sequence comparison of C1q from three different species have shown that the B chains have the strongest similarity. C1q was already present at embryonic day 14 (E14) and showed little change in abundance through six weeks postnatal. At E16, C1qB mRNA was present at high abundance in putative microglia/macrophages in cortical marginal and intermediate zones, and hippocampal analge.
Synonym: C1QB
- 分子量
- 25 kDa
- NCBI登录号
- NP_000482
- 途径
- Complement System
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