电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CLPS Protein (His tag)

CLPS 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7321063
发货至: 中国
  • 抗原 See all CLPS 蛋白
    CLPS (Colipase, Pancreatic (CLPS))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    资源
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CLPS protein is labelled with His tag.
    原理
    Recombinant Rat CLPS/Colipase Protein (His Tag)
    序列
    Met1-Gln112
    产品特性
    A DNA sequence encoding the rat Clps (NP_037271.1) (Met1-Gln112) was expressed with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg protein as determined by the LAL method.
    Top Product
    Discover our top product CLPS 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CLPS (Colipase, Pancreatic (CLPS))
    别名
    CLPS/Colipase (CLPS 产品)
    别名
    CLPS Protein, 2200003J09Rik Protein, COLQ Protein, colipase Protein, colipase, pancreatic Protein, CLPS Protein, Clps Protein
    背景

    Background: Colipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five conserved disulphide bonds. Structural analogies have been recognised between a developmental protein, the pancreatic lipase C-terminal domain, the N-terminal domains of lipoxygenases and the C-terminal domain of alpha-toxin. Colipase can only be detected in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Colipase allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. Colipase is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilising as active conformation and considerably increasing the overall hydrophobic binding site.

    Synonym: CLPS,Colipase

    分子量
    11.9 kDa
    NCBI登录号
    NP_037271
    途径
    Lipid Metabolism
You are here: