F13A1 Protein (His tag)
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- 抗原 See all F13A1 蛋白
- F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This F13A1 protein is labelled with His tag.
- 原理
- Recombinant Human F13a/Factor XIIIa Protein (His Tag)
- 序列
- Gly39-Met732
- 产品特性
- Recombinant Human Coagulation Factor XIII A Chain is produced by our Mammalian expression system and the target gene encoding Gly39-Met732 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product F13A1 蛋白
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Coagulation Factor XIII, A1 Polypeptide (F13A1) (AA 1-732) protein (GST tag)
F13A1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Coagulation Factor XIII, A1 Polypeptide (F13A1) (AA 39-732) protein (His tag)Crystallography grade F13A1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor XIII, A1 Polypeptide (F13A1) (AA 39-732) protein (His tag)Crystallography grade F13A1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor XIII, A1 Polypeptide (F13A1) protein (Myc-DYKDDDDK Tag)F13A1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 50 mM NaCl,5 % Sucrose, 1 % Tween 20 (v/v),0.3 % Histidine (w/v), pH 8.0.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))
- 别名
- F13a/Factor XIIIa (F13A1 产品)
- 别名
- F13a Protein, f13a1 Protein, wu:fo83d04 Protein, zgc:153334 Protein, F13A1 Protein, F13A Protein, 1200014I03Rik Protein, AI462306 Protein, coagulation factor XIII A1 chain Protein, coagulation factor XIII, A1 polypeptide b Protein, coagulation factor XIII A chain Protein, coagulation factor XIII, A1 subunit Protein, F13a1 Protein, f13a1b Protein, F13A1 Protein
- 背景
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Background: Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is composed of just 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits, and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.
Synonym: Coagulation Factor XIII A Chain, Coagulation Factor XIIIa, Protein-Glutamine Gamma-Glutamyltransferase A Chain, Transglutaminase A Chain, F13A1, F13A
- 分子量
- 80.3 kDa
- UniProt
- P00488
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