F13A1 产品
(Coagulation Factor XIII, A1 Polypeptide (F13A1))
Categories
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits\; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008].
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Featured F13A1 Categories
F13A1 抗体
High quality antibodies with extensive validation data.
F13A1 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
F13A1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended F13A1 抗体
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Reactivity
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Cat. No.
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Datasheet
Reactivity
Human
Application
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- (7)
Cat. No.
ABIN7433159
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
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- (10)
Cat. No.
ABIN7442897
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
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Validations
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Cat. No.
ABIN7440509
Quantity
100 μL
Datasheet
Datasheet
Recommended F13A1 ELISA试剂盒
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Reactivity
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Reactivity
Human
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Cat. No.
ABIN6965912
Quantity
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Reactivity
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- (1)
Cat. No.
ABIN6962106
Quantity
96 tests
Datasheet
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Reactivity
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Cat. No.
ABIN6954886
Quantity
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Datasheet
Datasheet
Recommended F13A1 蛋白
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Reactivity
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Source
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Cat. No.
ABIN1353305
Quantity
10 μg
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Reactivity
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Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3079512
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
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Validations
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Cat. No.
ABIN3124778
Quantity
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Datasheet
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Latest Publications for our F13A1 Products
: "Localized papular mucinosis with IgA nephropathy: a case report." in: Archives of dermatology, Vol. 147, Issue 5, pp. 599-602, (2011) (PubMed).: "Clinical significance of measuring blood coagulation factor XIIIA regularly and continuously in patients with Crohn's disease." in: Journal of gastroenterology and hepatology, Vol. 21, Issue 9, pp. 1407-11, (2006) (PubMed).
: "The coagulation cascade: initiation, maintenance, and regulation." in: Biochemistry, Vol. 30, Issue 43, pp. 10363-70, (1991) (PubMed).
Synonyms and alternative names related to F13A1
coagulation factor XIII A1 chain (F13a1), coagulation factor XIII, A1 polypeptide b (f13a1b), coagulation factor XIII A chain (F13A1), coagulation factor XIII, A1 subunit (F13a1), coagulation factor XIII A chain (F13a1), 1200014I03Rik, AI462306, F13a, F13A, f13a1, F13A1, wu:fo83d04, zgc:153334Protein level used designations for F13A1
- coagulation factor XIII A chain
- coagulation factor XIII, A1 subunit
- coagulation factor XIIIa
- protein-glutamine gamma-glutamyltransferase A chain
- transglutaminase A chain
- FX111a-87
- fo83d04
- coagulation factor XIII A1 subunit
- coagulation factor XIII, A1 polypeptide
- blood coagulation factor XIII A1 subunit
- coagulation factor XIIIA
- Coagulation factor XIII A chain
- FSF, A subunit
- TGase
- bA525O21.1 (coagulation factor XIII, A1 polypeptide)
- coagulation factor XIII, A polypeptide
- factor XIIIa
- fibrin stabilizing factor, A subunit
- fibrinoligase
- transglutaminase. plasma
- Factor XIIIA
- coagulation factor XIII, alpha subunit
- coagulation factor XIII A chain-like
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