Coagulation Factor X Protein (F10) (His tag)
-
- 抗原 See all Coagulation Factor X (F10) 蛋白
- Coagulation Factor X (F10)
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- Baculovirus infected Insect Cells
- 标记
- This Coagulation Factor X protein is labelled with His tag.
- 原理
- Recombinant Human Coagulation Factor X/F10 Protein (His Tag)
- 序列
- Met 1-Lys 488
- 产品特性
- A DNA sequence encoding the full length of human coagulation factor X (NP_000495.1) (Met 1-Lys 488) was expressed with a polyhistidine tag at the C-terminus.
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product F10 蛋白
-
Coagulation Factor X (F10) (AA 32-488) protein (GST tag)
F10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Coagulation Factor X (F10) protein (His tag)F10 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Coagulation Factor X (F10) (AA 183-488) protein (His tag)Crystallography grade F10 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor X (F10) (AA 235-488) protein (His tag)Crystallography grade F10 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor X (F10) (AA 41-179) protein (His tag)Crystallography grade F10 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor X (F10) (AA 184-481) protein (His tag)Crystallography grade F10 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor X (F10) (AA 232-481) protein (His tag)Crystallography grade F10 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor X (F10) (AA 41-180) protein (His tag)Crystallography grade F10 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor X (F10) (AA 41-488) protein (His tag)Crystallography grade F10 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Coagulation Factor X (F10) (AA 41-481) protein (His tag)Crystallography grade F10 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- Coagulation Factor X (F10)
- 别名
- Coagulation Factor X/F10 (F10 产品)
- 别名
- FX Protein, FXA Protein, Cf10 Protein, fX Protein, fi12c10 Protein, wu:fi12c10 Protein, F10 Protein, f10 Protein, coagulation factor X Protein, Coagulation factor X Protein, coagulation factor 10 L homeolog Protein, F10 Protein, f10 Protein, CpipJ_CPIJ012712 Protein, CpipJ_CPIJ014863 Protein, CpipJ_CPIJ016937 Protein, CpipJ_CPIJ017791 Protein, fa10 Protein, f10.L Protein
- 背景
-
Background: Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the coagulation cascade and blood clotting, as the first enzyme in the common pathway of thrombus formation. Factor X deficiency is one of the rarest of the inherited coagulation disorders. FX deficiency among the most severe of the rare coagulation defects, typically including hemarthroses, hematomas, and umbilical cord, gastrointestinal, and central nervous system bleeding. Factor X is synthesized in the liver as a mature heterodimer formed from a single-chain precursor, and vitamin K is essential for its synthesis. Factor X is activated into factor Xa (FXa) by both factor IX (with its cofactor, factor VIII in a complex known as intrinsic Xase) and factor VII (with its cofactor, tissue factor in a complex known as extrinsic Xase) through cleaving the activation propeptide. As the first member of the final common pathway or thrombin pathway, FXa converts prothrombin to thrombin in the presence of factor Va, Ca2+, and phospholipid during blood clotting and cleaves prothrombin in two places (an arg-thr and then an arg-ile bond). This process is optimized when factor Xa is complexed with activated cofactor V in the prothrombinase complex. Inborn deficiency of factor X is very uncommon, and may present with epistaxis (nose bleeds), hemarthrosis (bleeding into joints) and gastrointestinal blood loss. Apart from congenital deficiency, low factor X levels may occur occasionally in a number of disease states. Furhermore, factor X deficiency may be seen in amyloidosis, where factor X is adsorbed to the amyloid fibrils in the vasculature.
Synonym: Coagulation factor 10,coagulation factor X,FX,FXA
- 分子量
- 52.8 kDa
- NCBI登录号
- NP_000495
-
