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Coagulation Factor X 产品

(Coagulation Factor X (F10))
This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds\; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq, Jul 2008].

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Featured Coagulation Factor X Categories

Coagulation Factor X 抗体

High quality antibodies with extensive validation data.

Coagulation Factor X ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Coagulation Factor X 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Coagulation Factor X 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (5)
Cat. No. ABIN7432706
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IHC (p), ID, IEP
Validations
  • (3)
Cat. No. ABIN574160
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN7266422
Quantity 100 μL
Datasheet Datasheet

Recommended Coagulation Factor X ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6954878
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965901
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965903
Quantity 96 tests
Datasheet Datasheet

Recommended Coagulation Factor X 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353291
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320491
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3079915
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Coagulation Factor X Products

Posthuma, Posma, van Oerle, Leenders, van Gorp, Jaminon, Mackman, Heitmeier, Schurgers, Ten Cate, Spronk: "Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice." in: Scientific reports, Vol. 9, Issue 1, pp. 3909, (2019) (PubMed).

Wang, Braun, Zhang, Norström, Thorlacius: "Thrombin generation in abdominal sepsis is Rho-kinase-dependent." in: Biochemical and biophysical research communications, Vol. 460, Issue 3, pp. 691-6, (2015) (PubMed).

Wang, Braun, Zhang, Norström, Thorlacius: "Monocytes regulate systemic coagulation and inflammation in abdominal sepsis." in: American journal of physiology. Heart and circulatory physiology, Vol. 308, Issue 5, pp. H540-7, (2015) (PubMed).

Khare, Hillestad, Xu, Byrnes, Barry: "Circulating antibodies and macrophages as modulators of adenovirus pharmacology." in: Journal of virology, Vol. 87, Issue 7, pp. 3678-86, (2013) (PubMed).

Sudduth, Powell, Smith, Greenstein, Wilcock: "Induction of hyperhomocysteinemia models vascular dementia by induction of cerebral microhemorrhages and neuroinflammation." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 5, pp. 708-15, (2013) (PubMed).

Synonyms and alternative names related to Coagulation Factor X

coagulation factor X (F10), coagulation factor X (f10), coagulation factor X (CpipJ_CPIJ012712), coagulation factor X (CpipJ_CPIJ014863), coagulation factor X (CpipJ_CPIJ016937), coagulation factor X (CpipJ_CPIJ017791), Coagulation factor X (fa10), coagulation factor 10 L homeolog (f10.L), Cf10, F10, f10, fi12c10, FX, fX, FXA, wu:fi12c10

Protein level used designations for Coagulation Factor X

  • Stuart-Prower factor
  • factor Xa
  • prothrombinase
  • stuart factor
  • coagulation factor 10
  • VAP
  • factor XA light chain
  • virus activating protease
  • virus-activating protease
  • coagulation factor X
  • vitamin K dependent serine protease
  • coagulation factor X preproprotein
  • blood coagulation factor X
  • Coagulation factor X
  • coagulation factor 10 L homeolog
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