CD68 Protein (His tag,Fc Tag)
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- 抗原 See all CD68 蛋白
- CD68 (CD68 Molecule (CD68))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD68 protein is labelled with His tag,Fc Tag.
- 原理
- Recombinant Human CD68/Macrosialin Protein (His & Fc Tag)
- 序列
- Met 1-Ser 319
- 产品特性
- A DNA sequence encoding the human CD68 (NP_001242.2) extracellular domain (Met 1-Ser 319) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
- 纯度
- > 96 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD68 蛋白
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CD68 Molecule (CD68) (AA 164-262) protein (GST tag)
CD68 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD68 Molecule (CD68) protein (His tag)CD68 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
CD68 Molecule (CD68) protein (Fc Tag)CD68 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD68 (CD68 Molecule (CD68))
- 别名
- CD68/Macrosialin (CD68 产品)
- 别名
- Lamp4 Protein, Scard1 Protein, gp110 Protein, GP110 Protein, LAMP4 Protein, SCARD1 Protein, CD68 molecule Protein, CD68 antigen Protein, Cd68 molecule Protein, CD68 Protein, Cd68 Protein
- 背景
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Background: Macrosialin, also known as CD68 and Gp110, is a single-pass type I membrane protein which belongs to the LAMP family. CD68 is highly expressed by blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts and endothelial cells. CD68 is expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 plays a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It is a commonly used marker for macrophages. However, a number of studies have shown that CD68 antibodies react with other hematopoietic and non-hematopoietic cell types, suggesting that CD68 may not be a macrophage-specific antigen. CD68 binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Synonym: GP110;LAMP4;SCARD1
- 分子量
- 59.6 kDa
- NCBI登录号
- NP_001242
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