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CD3D Protein (Fc Tag)

CD3D 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7320952
发货至: 中国
  • 抗原 See all CD3D 蛋白
    CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Cynomolgus
    资源
    • 11
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    人细胞
    标记
    This CD3D protein is labelled with Fc Tag.
    原理
    Recombinant Cynomolgus CD3d/CD3 delta Protein (Fc Tag)
    序列
    Phe22-Ala105
    产品特性
    Recombinant Cynomolgus CD3d is produced by our Mammalian expression system and the target gene encoding Phe22-Ala105 is expressed with a Fc tag at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD3D 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
    别名
    CD3d/CD3 delta (CD3D 产品)
    别名
    CD3-DELTA Protein, T3D Protein, CD3 Protein, T3d Protein, CD3d molecule Protein, CD3 antigen, delta polypeptide Protein, CD3D Protein, Cd3d Protein
    背景

    Background: T-cell surface glycoprotein CD3 delta chain (CD3D) is a single-pass type I membrane protein. CD3D, together with CD3-gamma, CD3-epsilon and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. CD3 chains are present as CD3gammaepsilon, deltaepsilon, and zetazeta dimers in the receptor complex and play critical roles in the antigen receptor assembly, transport to the cell surface, and the receptor-mediated signal transduction. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs(ITAMs). CD3D contains 1 ITAM domain and has been shown to interact with CD8A.

    Synonym: T-cell surface glycoprotein CD3 delta chain, T-cell receptor T3 delta chain, CD3d, CD3D

    分子量
    36.7 kDa
    UniProt
    Q95LI8
    途径
    TCR Signaling, CXCR4-mediated Signaling Events
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