CD207 Protein (His tag)
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- 抗原 See all CD207 蛋白
- CD207 (CD207 Molecule, Langerin (CD207))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This CD207 protein is labelled with His tag.
- 原理
- Recombinant Human Langerin/CD207 Protein (His Tag)
- 序列
- Tyr64-Pro328(Val278Ala)
- 产品特性
- Recombinant Human Langerin is produced by our Mammalian expression system and the target gene encoding Tyr64-Pro328(Val278Ala) is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CD207 蛋白
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CD207 Molecule, Langerin (CD207) (AA 1-328) protein (GST tag)
CD207 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD207 Molecule, Langerin (CD207) (AA 65-328) protein (His tag)CD207 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
CD207 Molecule, Langerin (CD207) protein (Myc-DYKDDDDK Tag)CD207 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD207 (CD207 Molecule, Langerin (CD207))
- 别名
- Langerin/CD207 (CD207 产品)
- 别名
- CD207 Protein, CLEC4K Protein, RGD1565913 Protein, CD207 molecule Protein, CD207 antigen Protein, CD207 Protein, Cd207 Protein
- 背景
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Background: Langerin (CD207) is a type II transmembrane glycoprotein which is member K of the C-type lectin domain family. Langerin is used as a marker for Langerhans cells (LCs) which represent the immature dendritic cells in the epidermis. Langerin is necessary and sufficient for Birbeck granule formation. Human langerin sequence contains a 43 aa cytoplasmic domain, a 21 aa transmembrane domain and a 264 aa extracellular domain (ECD) that contains a coiled-coil domain and a single C-type lectin domain. Human langerin shares 68 % , 62 %, 71 % aa identity with mouse, rat and bovine langerin ECD, respectively. Trimerization greatly increases the lectin binding affinity. Langerin internalizes endogenous proteins such as type I procollagen. Internalization by LC is thought to lead to suppression of self reactions. Langerin also mediates endocytosis of non-peptide antigens containing mannose, N-acetyl glucosamine and fucose that are expressed by mycobacteria and fungae.
Synonym: CD207 antigen, langerin, CD207, C-type lectin domain family 4 member K, C-type lectin domainfamily 4, member K
- 分子量
- 31.5 kDa
- UniProt
- Q9UJ71
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