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CD207 产品

(CD207 Molecule, Langerin (CD207))

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The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010].

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Featured CD207 Categories

CD207 抗体

High quality antibodies with extensive validation data.

CD207 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CD207 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD207 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (7)
Cat. No. ABIN7193631
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC, Neut
Validations
  • (4)
Cat. No. ABIN5611331
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), IF
Validations
  • (3)
Cat. No. ABIN5574254
Quantity 100 μL
Datasheet Datasheet

Recommended CD207 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1569037
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883601
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385895
Quantity 96 tests
Datasheet Datasheet

Recommended CD207 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348571
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3118961
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3126866
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CD207 Products

Tanei, Hasegawa et al.: "Immunohistopathological Analysis of Immunoglobulin E-Positive Epidermal Dendritic Cells with House Dust Mite Antigens in Naturally Occurring Skin Lesions of Adult and Elderly Patients with Atopic ..." in: Dermatopathology (Basel, Switzerland), Vol. 8, Issue 3, pp. 426-441, (2021) (PubMed).

Yasuda, Ura, Taniguchi, Yoshida: "Intradermal Delivery of Antigens Enhances Specific IgG and Diminishes IgE Production: Potential Use for Vaccination and Allergy Immunotherapy." in: PLoS ONE, Vol. 11, Issue 12, pp. e0167952, (2016) (PubMed).

De Jesus, Ostroff, Levitz, Bartling, Mantis: "A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling β-glucan microparticles." in: PLoS ONE, Vol. 9, Issue 3, pp. e91002, (2014) (PubMed).

Gerber, Münst, Schlapbach, Shafighi, Kiermeir, Hüsler, Hunger: "High expression of FOXP3 in primary melanoma is associated with tumour progression." in: The British journal of dermatology, Vol. 170, Issue 1, pp. 103-9, (2014) (PubMed).

Elnekave, Furmanov, Shaul, Capucha, Eli-Berchoer, Zelentsova, Clausen, Hovav: "Second-generation Langerhans cells originating from epidermal precursors are essential for CD8+ T cell priming." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 4, pp. 1395-403, (2014) (PubMed).

Flacher, Tripp, Mairhofer, Steinman, Stoitzner, Idoyaga, Romani: "Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance." in: EMBO molecular medicine, Vol. 6, Issue 9, pp. 1191-204, (2014) (PubMed).

Sparber, Tripp, Komenda, Scheffler, Clausen, Huber, Romani, Stoitzner: "The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells." in: The Journal of investigative dermatology, Vol. 135, Issue 1, pp. 119-29, (2014) (PubMed).

Voisin, Mairhofer, Chen, Stoitzner, Mueller, Flacher: "Anatomical distribution analysis reveals lack of Langerin+ dermal dendritic cells in footpads and tail of C57BL/6 mice." in: Experimental dermatology, Vol. 23, Issue 5, pp. 354-6, (2014) (PubMed).

Bonetti, Bacci, Santosuosso, Mazzanti, Aldinucci, Ballerini, Guasti, Calosi, Bosi, Romagnoli: "Rosiglitazone promotes the differentiation of Langerhans cells and inhibits that of other dendritic cell types from CD133 positive hematopoietic precursors." in: Histology and histopathology, Vol. 29, Issue 3, pp. 323-32, (2014) (PubMed).

Larbi, Mitjavila-Garcia, Flamant, Valogne, Clay, Usunier, lHomme, Féraud, Casal, Gobbo, Divers, Chapel, Turhan, Bennaceur-Griscelli, Haddad: "Generation of multipotent early lymphoid progenitors from human embryonic stem cells." in: Stem cells and development, Vol. 23, Issue 24, pp. 2983-95, (2014) (PubMed).

Synonyms and alternative names related to CD207

CD207 molecule (CD207), CD207 antigen (Cd207), CD207 molecule (Cd207), CD207, CLEC4K, RGD1565913

Protein level used designations for CD207

  • CD207 molecule, langerin
  • CD207 antigen, langerin
  • C-type lectin domain family 4 member K
  • Langerhans cell specific c-type lectin
  • langerin
  • C-type lectin domain family 4, member K
  • CD 207 antigen
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