Caspase 7 Protein (His tag)
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- 抗原 See all Caspase 7 (CASP7) 蛋白
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Caspase 7 protein is labelled with His tag.
- 原理
- Recombinant Human CASP7/caspase 7 Protein (His Tag)
- 序列
- Met 1-Gln 303
- 产品特性
- A DNA sequence encoding the human CASP7 (P55210-1) (Met 1-Gln 303) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CASP7 蛋白
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Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 1-100) protein (GST tag)
CASP7 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 1-303) protein (His tag)CASP7 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 207-303) protein (GST tag)CASP7 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) protein (His tag)Crystallography grade CASP7 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) protein (His tag)Crystallography grade CASP7 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM HEPES, 100 mM NaCl, 1 mM EDTA, 0.10 % Sucrose, 0.1 % chaps, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
- 别名
- CASP7/caspase 7 (CASP7 产品)
- 别名
- xCaspase-7 Protein, caspase-7 Protein, caspase7 Protein, cmh-1 Protein, ice-lap3 Protein, mch3 Protein, CASP7 Protein, AI314680 Protein, CMH-1 Protein, ICE-IAP3 Protein, Mch3 Protein, mCASP-7 Protein, CASP-7 Protein, ICE-LAP3 Protein, LICE2 Protein, MCH3 Protein, Caspase-7 Protein, MCH3/SCA-2 Protein, SCA-2 Protein, caspase 7 Protein, caspase-7 Protein, caspase 7 S homeolog Protein, CASP7 Protein, xcaspase-7 Protein, casp7 Protein, casp7.S Protein, Casp7 Protein
- 背景
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Background: Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family. Caspases play a role in the signal transduction pathways of apoptosis, necrosis and inflammation. There are two major classes of caspases: initiators and effectors. The initiator isoforms (caspases-1,-4,-5,-8,-9,-10,-11,-12) are activated by, and interact with, upstream adaptor molecules through protein-protein interaction domains known as CARD and DED. Effector caspases (-3,-6,-7) are responsible for cleaving downstream substrates and are sometimes referred to as the executioner caspases. Caspase 7 exists in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. Caspase 7 cannot be detected in the brain. Caspase 7 functions in the activation cascade of caspases responsible for apoptosis execution. It cleaves and activates sterol regulatory element binding proteins (SREBPs). It proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp- -Gly-217' bond. Overexpression promotes programmed cell death.
Synonym: CASP-7,CMH-1,ICE-LAP3,LICE2,MCH3
- 分子量
- 35kDa
- 途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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