E-cadherin Protein (Fc Tag)
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- 抗原 See all E-cadherin (CDH1) 蛋白
- E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This E-cadherin protein is labelled with Fc Tag.
- 原理
- Recombinant Rat E-Cadherin/CDH1 Protein (Fc Tag)
- 序列
- Met1-Ala713
- 产品特性
- A DNA sequence encoding the rat CDH1 (Q9R0T4) (Met1-Ala713) was expressed with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 75 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product CDH1 蛋白
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Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 1-882) protein (GST tag)
CDH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 381-480) protein (GST tag)CDH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 155-707) protein (His tag)CDH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Active) protein (His tag)CDH1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE Active
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) protein (His tag)CDH1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 731-882) protein (His tag)Crystallography grade CDH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 734-884) protein (His tag)Crystallography grade CDH1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 155-709) protein (His tag)Crystallography grade CDH1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 157-709) protein (His tag)Crystallography grade CDH1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (AA 751-882) protein (rho-1D4 tag)Crystallography grade CDH1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
- 别名
- E-Cadherin/CDH1 (CDH1 产品)
- 别名
- Arc-1 Protein, CD324 Protein, CDHE Protein, ECAD Protein, LCAM Protein, UVO Protein, E-cadherin Protein, cdh1 Protein, si:dz180o5.2 Protein, uvo Protein, lcam Protein, E-Cad Protein, XBcad Protein, l-cam Protein, xcdh1 Protein, cdhc-A Protein, xb-cad Protein, XTCAD-1 Protein, c-cadherin Protein, cadherin-1 Protein, uvomorulin Protein, XB-cadherin Protein, arc-1 Protein, cd324 Protein, cdhe Protein, ecad Protein, AA960649 Protein, E-cad Protein, Ecad Protein, L-CAM Protein, Um Protein, cadherin 1 Protein, si:busm1-180o5.2 Protein, cadherin 1, type 1, E-cadherin (epithelial) Protein, cadherin 1, type 1 S homeolog Protein, CDH1 Protein, si:busm1-180o5.2 Protein, cdh1 Protein, Cdh1 Protein, cdh1.S Protein
- 背景
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Background: Cadherins are calcium-dependent cell adhesion proteins which preferentially interact with themselves in a homophilic manner in connecting cells, and thus may contribute to the sorting of heterogeneous cell type. E-cadherin (E-Cad), also known as CDH1 and CD324, is a calcium-dependent cell adhesion molecule the intact function of which is crucial for the establishment and maintenance of epithelial tissue polarity and structural integrity. Mutations in CDH1 occur in diffuse type gastric cancer, lobular breast cancer, and endometrial cancer. In human cancers, partial or complete loss of E-cadherin expression correlates with malignancy. During apoptosis or with calcium influx, E-Cad is cleaved by the metalloproteinase to produce fragments of about 38 kDa (E-CAD/CTF1), 33 kDa (E-CAD/CTF2) and 29 kDa (E-CAD/CTF3), respectively. E-Cad has been identified as a potent invasive suppressor, as downregulation of E-cadherin expression is involved in dysfunction of the cell-cell adhesion system, and often correlates with strong invasive potential and poor prognosis of human carcinomas.
Synonym: CDH1,E-cad,CD324
- 分子量
- 103.8 kDa
- UniProt
- Q9R0T4
- 途径
- WNT signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation
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