CLEC10A Protein (Fc Tag)
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- 抗原 See all CLEC10A 蛋白
- CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CLEC10A protein is labelled with Fc Tag.
- 原理
- Recombinant Human CLEC10A/CD301 Protein (Fc Tag)
- 序列
- Gln61-His292
- 产品特性
- A DNA sequence encoding the human CLEC10A (Q8IUN9-2) (Gln61-His292) was expressed, with the fused Fc region of human IgG1 at the N-terminus.
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CLEC10A 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
- 别名
- CLEC10A/CD301 (CLEC10A 产品)
- 别名
- CLEC10A Protein, CD301 Protein, CLECSF13 Protein, CLECSF14 Protein, HML Protein, HML2 Protein, MGL Protein, CD301a Protein, M-ASGP-BP-1 Protein, Mgl Protein, Mgl1 Protein, Mgll Protein, C-type lectin domain family 10 member A Protein, C-type lectin domain containing 10A Protein, C-type lectin domain family 10, member A Protein, LOC607405 Protein, CLEC10A Protein, Clec10a Protein
- 背景
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Background: CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs, CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.
Synonym: C-Type Lectin Domain Family 10 Member A, C-Type Lectin Superfamily Member 14, Macrophage Lectin 2, CD301, CLEC10A, CLECSF13, CLECSF14, HML
- 分子量
- 54.6 kDa
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