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CLEC10A Protein (Fc Tag)

CLEC10A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 86 % as determined by SDS-PAGE
产品编号 ABIN7194472
发货至: 中国
  • 抗原 See all CLEC10A 蛋白
    CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
    蛋白类型
    Recombinant
    宿主
    • 13
    • 4
    • 1
    小鼠
    资源
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This CLEC10A protein is labelled with Fc Tag.
    原理
    Recombinant Mouse CLEC10A/CD301 Protein (Fc Tag)
    序列
    Gln 58-Ser 305
    产品特性
    A DNA sequence encoding the extracellular domain of mouse CLEC10A (NP_001191181.1) (Gln 58-Ser 305) was fused with the Fc region of human IgG1 at the N-terminus.
    纯度
    > 86 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product CLEC10A 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
    别名
    CLEC10A/CD301 (CLEC10A 产品)
    别名
    CLEC10A Protein, CD301 Protein, CLECSF13 Protein, CLECSF14 Protein, HML Protein, HML2 Protein, MGL Protein, CD301a Protein, M-ASGP-BP-1 Protein, Mgl Protein, Mgl1 Protein, Mgll Protein, C-type lectin domain family 10 member A Protein, C-type lectin domain containing 10A Protein, C-type lectin domain family 10, member A Protein, LOC607405 Protein, CLEC10A Protein, Clec10a Protein
    背景

    Background: CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs, CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.

    Synonym: CD301a,M-ASGP-BP-1,Mgl,Mgl1

    分子量
    56.7 kDa
    NCBI登录号
    NP_001191181
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