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BMPR1B Protein (AA 149-502) (GST tag,His tag)

BMPR1B 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317106
发货至: 中国
  • 抗原 See all BMPR1B 蛋白
    BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))
    蛋白类型
    Recombinant
    产品特性
    AA 149-502
    宿主
    • 11
    • 4
    资源
    • 7
    • 4
    • 2
    • 1
    • 1
    Baculovirus infected Insect Cells
    标记
    This BMPR1B protein is labelled with GST tag,His tag.
    原理
    Recombinant Human BMPR1B/ALK-6 Protein (aa 149-502, His&GST Tag)
    序列
    Arg 149-Leu 502
    产品特性
    A DNA sequence encoding the human ALK6 (NP_001194.1) cytoplasmic domain (Arg 149-Leu 502) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product BMPR1B 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as sterile 50 mM Tris, 100 mM NaCl, pH 8.5, 20 % glycerol, 0.3 mM DTT
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))
    别名
    BMPR1B/ALK-6 (BMPR1B 产品)
    别名
    ALK6 Protein, BMPR-IB Protein, FecB Protein, alk-6 Protein, alk6 Protein, cdw293 Protein, alk6b Protein, zgc:172219 Protein, BMPR1B Protein, AI385617 Protein, ALK-6 Protein, AV355320 Protein, Acvrlk6 Protein, Alk6 Protein, BMPR-1B Protein, CFK-43a Protein, SKR6 Protein, BR1b Protein, alk6tr Protein, bmpr1b Protein, zALK-6 Protein, zgc:92220 Protein, CDw293 Protein, BMP15 Protein, BMPRIB Protein, RPK-1 Protein, bone morphogenetic protein receptor type 1B Protein, bone morphogenetic protein receptor, type IBb Protein, bone morphogenetic protein receptor, type 1B Protein, bone morphogenetic protein receptor, type IBa Protein, BMPR1B Protein, bmpr1b Protein, bmpr1bb Protein, Bmpr1b Protein, bmpr1ba Protein
    背景

    Background: BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMPR1B is the major transducer of signals in precartilaginous condensations as demonstrated in experiments using constitutively active BMPR1B receptors. BMPR1B is a more effective trasducer of GDF5 than BMPR1A. Unlike BMPR1A null mice, which die at an early embryonic stage, BMPR1B null mice are viable.

    Synonym: ALK-6,ALK6,CDw293

    分子量
    68.3 kDa
    NCBI登录号
    NP_001194
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