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BMPR1B Protein (Fc Tag)

BMPR1B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > (88.3+9.9) % as determined by SDS-PAGE
产品编号 ABIN7194418
发货至: 中国
  • 抗原 See all BMPR1B 蛋白
    BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))
    蛋白类型
    Recombinant
    宿主
    • 12
    • 3
    小鼠
    资源
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This BMPR1B protein is labelled with Fc Tag.
    原理
    Recombinant Mouse BMPR1B/ALK-6 Protein (Fc Tag)
    序列
    Lys14-Lys126
    产品特性
    A DNA sequence encoding the mouse Bmpr1b (NP_031586.1) (Lys14-Lys126) was expressed with the Fc region of human IgG1 at the C-terminus.
    纯度
    > (88.3+9.9) % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product BMPR1B 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))
    别名
    BMPR1B/ALK-6 (BMPR1B 产品)
    别名
    ALK6 Protein, BMPR-IB Protein, FecB Protein, alk-6 Protein, alk6 Protein, cdw293 Protein, alk6b Protein, zgc:172219 Protein, BMPR1B Protein, AI385617 Protein, ALK-6 Protein, AV355320 Protein, Acvrlk6 Protein, Alk6 Protein, BMPR-1B Protein, CFK-43a Protein, SKR6 Protein, BR1b Protein, alk6tr Protein, bmpr1b Protein, zALK-6 Protein, zgc:92220 Protein, CDw293 Protein, BMP15 Protein, BMPRIB Protein, RPK-1 Protein, bone morphogenetic protein receptor type 1B Protein, bone morphogenetic protein receptor, type IBb Protein, bone morphogenetic protein receptor, type 1B Protein, bone morphogenetic protein receptor, type IBa Protein, BMPR1B Protein, bmpr1b Protein, bmpr1bb Protein, Bmpr1b Protein, bmpr1ba Protein
    背景

    Background: BMPR1B(bone morphogenetic protein receptor, type IB), also known as ALK6, is a a member of the bone morphogenetic protein (BMP) receptor family. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. BMPR1B is the major transducer of signals in precartilaginous condensations as demonstrated in experiments using constitutively active BMPR1B receptors. BMPR1B is a more effective trasducer of GDF5 than BMPR1A. Unlike BMPR1A null mice, which die at an early embryonic stage, BMPR1B null mice are viable.

    Synonym: Acvrlk6,AI385617,ALK-6,Alk6,AV355320,BMPR-1B,BMPR-IB,CFK-43a,SKR6

    分子量
    39.4 kDa
    NCBI登录号
    NP_031586
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