BCL6 Protein (AA 1-150) (TRX tag,His tag)
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- 抗原 See all BCL6 蛋白
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-150
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This BCL6 protein is labelled with TRX tag,His tag.
- 原理
- Recombinant Human BCL6/B-cell CLL lymphoma 6 Protein (aa 1-150, His & Trx Tag)
- 序列
- Met 1-Met 150
- 产品特性
- A DNA sequence encoding the human BCL6 (P41182) N-terminal fragment (Met 1-Met 150) was fused with a Trx and a polyhistidine tag at the N-terminus.
- 纯度
- > 92 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BCL6 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 10 % glycerol, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
- 别名
- BCL6/B-cell CLL lymphoma 6 (BCL6 产品)
- 别名
- bcl5 Protein, laz3 Protein, bcl6a Protein, znf51 Protein, zbtb27 Protein, MGC132260 Protein, Bcl5 Protein, BCL5 Protein, BCL6A Protein, LAZ3 Protein, ZBTB27 Protein, ZNF51 Protein, B-cell CLL/lymphoma 6 L homeolog Protein, B-cell CLL/lymphoma 6 Protein, B cell leukemia/lymphoma 6 Protein, bcl6.L Protein, bcl6 Protein, BCL6 Protein, Bcl6 Protein
- 背景
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Background: The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon specific DNA-binding and the presence of an intact N-terminal half of the protein.
Synonym: BCL5;BCL6A;LAZ3;ZBTB27;ZNF51
- 分子量
- 34.2 kDa
- UniProt
- P41182
- 途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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