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BCL6 Protein (AA 1-150) (TRX tag,His tag)

BCL6 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 92 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317419
发货至: 中国
  • 抗原 See all BCL6 蛋白
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    蛋白类型
    Recombinant
    产品特性
    AA 1-150
    宿主
    • 7
    • 1
    资源
    • 3
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This BCL6 protein is labelled with TRX tag,His tag.
    原理
    Recombinant Human BCL6/B-cell CLL lymphoma 6 Protein (aa 1-150, His & Trx Tag)
    序列
    Met 1-Met 150
    产品特性
    A DNA sequence encoding the human BCL6 (P41182) N-terminal fragment (Met 1-Met 150) was fused with a Trx and a polyhistidine tag at the N-terminus.
    纯度
    > 92 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product BCL6 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, 10 % glycerol, pH 8.0
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    别名
    BCL6/B-cell CLL lymphoma 6 (BCL6 产品)
    别名
    bcl5 Protein, laz3 Protein, bcl6a Protein, znf51 Protein, zbtb27 Protein, MGC132260 Protein, Bcl5 Protein, BCL5 Protein, BCL6A Protein, LAZ3 Protein, ZBTB27 Protein, ZNF51 Protein, B-cell CLL/lymphoma 6 L homeolog Protein, B-cell CLL/lymphoma 6 Protein, B cell leukemia/lymphoma 6 Protein, bcl6.L Protein, bcl6 Protein, BCL6 Protein, Bcl6 Protein
    背景

    Background: The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon specific DNA-binding and the presence of an intact N-terminal half of the protein.

    Synonym: BCL5;BCL6A;LAZ3;ZBTB27;ZNF51

    分子量
    34.2 kDa
    UniProt
    P41182
    途径
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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