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BCL6 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

BCL6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2715204
发货至: 中国
  • 抗原 See all BCL6 蛋白
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 1
    宿主
    • 7
    • 1
    资源
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This BCL6 protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Bcl-6 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product BCL6 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    别名
    Bcl-6 (BCL6 产品)
    别名
    bcl5 Protein, laz3 Protein, bcl6a Protein, znf51 Protein, zbtb27 Protein, MGC132260 Protein, Bcl5 Protein, BCL5 Protein, BCL6A Protein, LAZ3 Protein, ZBTB27 Protein, ZNF51 Protein, B-cell CLL/lymphoma 6 L homeolog Protein, B-cell CLL/lymphoma 6 Protein, B cell leukemia/lymphoma 6 Protein, bcl6.L Protein, bcl6 Protein, BCL6 Protein, Bcl6 Protein
    背景
    The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
    分子量
    78.7 kDa
    NCBI登录号
    NP_001697
    途径
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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