Liver Arginase Protein (His tag)
-
- 抗原 See all Liver Arginase (ARG1) 蛋白
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This Liver Arginase protein is labelled with His tag.
- 原理
- Recombinant Human Arginase-1 Protein (His Tag)
- 序列
- 1M-322K
- 产品特性
- A DNA sequence encoding the human Arginase-1 (1M-322K) was expressed with a polyhistidine tag at the N-terminus.
- 纯度
- >90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product ARG1 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Frozen, Liquid
- 缓冲液
- Liquid with sterile 25 mM Tris-HCl+150 mM KCl+1 mM DTT+20 % glycerol
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Samples are stable for up to twelve months from date of receipt at -70°C.Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
- 抗原
- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
- 别名
- Arginase-1 (ARG1 产品)
- 别名
- SI:zC146F4.4 (novel protein with NUDIX domain) Protein, si:ch211-146f4.3 Protein, argi1 Protein, AI Protein, AI256583 Protein, Arg-1 Protein, PGIF Protein, arginase 1 Protein, arginase Protein, Arginase-1 Protein, arginase, liver Protein, L-arginase Protein, arg1 Protein, PGTG_16455 Protein, argi1 Protein, ARG1 Protein, Arg1 Protein
- 背景
-
Background: Arginase 1, also known as liver arginase, is a binuclear manganese metalloenzyme. It is a key enzyme of the urea cycle that catalyses the conversion of L-arginine into L-ornithine and urea, the final cytosolic reaction of urea formation in the mammalian liver. Arginase 1 is abundantly expressed in liver, but it is also expressed in cells and tissues that lack a complete urea cycle, including lung. Arginase is a critical regulator of nitric oxide synthesis and vascular function. It is implicated in a variety of human diseases including vascular disease, pulmonary disease, infectious disease, immune cell function and cancer. In humans, hereditary defects in arginase result in an accumulation of arginine in the blood known as hyperarginemia. Arginase deficiency can also result in the accumulation of nitrogen in the form of ammonia, which results in hyperammonemia.
Synonym: ARG1,Al,Arginase 1,Arginase liver,
- 分子量
- 36.9kDa
- UniProt
- P05089
- 途径
- Cellular Response to Molecule of Bacterial Origin
-