ACVR2B Protein (His tag,Fc Tag)
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- 抗原 See all ACVR2B 蛋白
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This ACVR2B protein is labelled with His tag,Fc Tag.
- 原理
- Recombinant Human Activin Receptor 2B/ACVR2B Protein (Fc & His Tag)(Active)
- 序列
- Ser19-Thr134
- 产品特性
- Recombinant Human Activin Receptor Type 2B is produced by our Mammalian expression system and the target gene encoding Ser19-Thr134 is expressed with a Fc, 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human/Mouse/Rat Activin A(Cat: PKSH033807) at 5μg/ml(100 μl/well) can bind Human ACVR2B-His. The ED50 of Human ACVR2B-His is 20.58 ng/ml .
- Top Product
- Discover our top product ACVR2B 蛋白
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Activin A Receptor, Type IIB (ACVR2B) (AA 161-512) (Active) protein (GST tag)
ACVR2B 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Activin A Receptor, Type IIB (ACVR2B) (AA 1-303) protein (GST tag)ACVR2B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor, Type IIB (ACVR2B) (AA 21-120) protein (GST tag)ACVR2B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor, Type IIB (ACVR2B) (Active) protein (His tag,Fc Tag)ACVR2B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Activin A Receptor, Type IIB (ACVR2B) (Active) protein (His tag)ACVR2B 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE Active
Activin A Receptor, Type IIB (ACVR2B) (AA 159-512) protein (His tag)Crystallography grade ACVR2B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 19-137) protein (His tag)Crystallography grade ACVR2B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 159-536) protein (His tag)Crystallography grade ACVR2B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 19-137) protein (His tag)Crystallography grade ACVR2B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IIB (ACVR2B) (AA 19-512) protein (rho-1D4 tag)Crystallography grade ACVR2B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- 别名
- Activin Receptor 2B/ACVR2B (ACVR2B 产品)
- 别名
- ACVR2B Protein, XAR1 Protein, actr-iib Protein, actriib Protein, ACTRIIB Protein, ActR-IIB Protein, HTX4 Protein, ActRIIB Protein, actr2b Protein, actrIIb Protein, wu:fj97d11 Protein, activin A receptor type 2B Protein, activin A receptor type 2B L homeolog Protein, activin A receptor type 2Ba Protein, activin receptor IIB Protein, ACVR2B Protein, acvr2b Protein, acvr2b.L Protein, Acvr2b Protein, acvr2ba Protein
- 背景
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Background: Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity, and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB, also known as ActRIIB, is a type II receptor containing an extracellular domain (ECD), a transmembrane segment, and a cytoplasmic region that includes the kinase domain. ActRIIB is a receptor for activin A, activin B and inhibin A. Multiple ActRIIB isoforms can also be generated, which bind activin isoforms with different affinities.
Synonym: Activin Receptor Type-2B, Activin Receptor Type IIB, ACTR-IIB, ACVR2B,Bone Morphogenetic Protein Receptor Type-2, BMP Type-2 Receptor, BMPR-3, Bone Morphogenetic Protein Receptor Type II, BMP Type II Receptor
- 分子量
- 41.3 kDa
- UniProt
- Q13705
- 途径
- Hormone Transport, Cancer Immune Checkpoints
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