Activin A Receptor Type IB/ALK-4 Protein (His tag)
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- 抗原 See all Activin A Receptor Type IB/ALK-4 (ACVR1B) 蛋白
- Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This Activin A Receptor Type IB/ALK-4 protein is labelled with His tag.
- 原理
- Recombinant Human ALK4/ACVR1B Protein (His Tag)(Active)
- 序列
- Ser24-Glu126
- 产品特性
- Recombinant Human Activin Receptor Type-1B is produced by our Mammalian expression system and the target gene encoding Ser24-Glu126 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human TDGF1-Fc(Cat: PKSH033100) at 10μg/ml(100 μl/well) can bind Human ACVR1B-His. The ED50 of Human ACVR1B-His is 4.7 ug/ml.
- Top Product
- Discover our top product ACVR1B 蛋白
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Activin A Receptor, Type IB (ACVR1B) (AA 150-505) (Active) protein (GST tag)
ACVR1B 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Activin A Receptor, Type IB (ACVR1B) protein (Fc Tag)ACVR1B 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Activin A Receptor, Type IB (ACVR1B) (AA 24-126) protein (His-IF2DI Tag)ACVR1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Activin A Receptor, Type IB (ACVR1B) (AA 1-505) protein (GST tag)ACVR1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor, Type IB (ACVR1B) (AA 24-126) protein (GST tag)ACVR1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor, Type IB (ACVR1B) (Active) protein (Fc Tag)ACVR1B 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Activin A Receptor, Type IB (ACVR1B) (AA 150-505) protein (His tag)Crystallography grade ACVR1B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IB (ACVR1B) (AA 24-126) protein (His tag)Crystallography grade ACVR1B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IB (ACVR1B) (AA 150-505) protein (His tag)Crystallography grade ACVR1B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IB (ACVR1B) (AA 24-126) protein (His tag)Crystallography grade ACVR1B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))
- 别名
- ALK4/ACVR1B (ACVR1B 产品)
- 别名
- ACVR1B Protein, alk4 Protein, skr2 Protein, alk-4 Protein, xalk4 Protein, actrib Protein, acvrlk4 Protein, DKFZp469A1614 Protein, 6820432J04 Protein, ActR-IB Protein, ActRIB Protein, Acvrlk4 Protein, Alk4 Protein, SKR2 Protein, ACTRIB Protein, ACVRLK4 Protein, ALK4 Protein, Skr2 Protein, axis Protein, taram-a Protein, tarama Protein, wu:fb75f01 Protein, activin A receptor type 1B Protein, Activin receptor type-1B Protein, activin A receptor, type IB Protein, activin A receptor, type 1B Protein, activin A receptor type 1Ba Protein, ACVR1B Protein, acvr1b Protein, acv1b Protein, Acvr1b Protein, acvr1ba Protein
- 背景
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Background: Activin Receptor Type-1B (ACVR1B) is a single-pass type I membrane protein that belongs to the protein kinase superfamily. ACVR1B contains one GS domain and one protein kinase domain and is expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver. ACVR1B acts as a transducer of activin or activin like ligands signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B, ACVR2A or ACVR2B activating ACVR1B through phosphorylation of its regulatory GS domain. They go on to recruit the R-SMADs, SMAD2 and SMAD3. ACVR1B also transducers signals of nodal, GDF-1, and Vg1. Mutations in ACVR1B are associated with pituitary tumors.
Synonym: Activin Receptor Type-1B, Activin Receptor Type IB, ACTR-IB, Activin Receptor-Like Kinase 4, ALK-4, Serine/Threonine-Protein Kinase Receptor R2, SKR2, ACVR1B, ACVRLK4, ALK4
- 分子量
- 12.5 kDa
- UniProt
- P36896
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