Activin A Receptor Type IB/ALK-4 Protein (Fc Tag)
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- 抗原 See all Activin A Receptor Type IB/ALK-4 (ACVR1B) 蛋白
- Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This Activin A Receptor Type IB/ALK-4 protein is labelled with Fc Tag.
- 原理
- Recombinant Rat ALK4/ACVR1B Protein (Fc Tag)(Active)
- 序列
- Met1-Glu126
- 产品特性
- A DNA sequence encoding the rat ACVR1B (Met1-Glu126) was expressed with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Biological Activity Comment
- Measured by its ability to bind with rat TDGF1-His in a functional ELISA.
- Top Product
- Discover our top product ACVR1B 蛋白
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Activin A Receptor, Type IB (ACVR1B) (AA 150-505) (Active) protein (GST tag)
ACVR1B 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Activin A Receptor, Type IB (ACVR1B) protein (Fc Tag)ACVR1B 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Activin A Receptor, Type IB (ACVR1B) (AA 24-126) protein (His-IF2DI Tag)ACVR1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Activin A Receptor, Type IB (ACVR1B) (AA 1-505) protein (GST tag)ACVR1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor, Type IB (ACVR1B) (AA 24-126) protein (GST tag)ACVR1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Activin A Receptor, Type IB (ACVR1B) (AA 150-505) protein (His tag)Crystallography grade ACVR1B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IB (ACVR1B) (AA 24-126) protein (His tag)Crystallography grade ACVR1B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IB (ACVR1B) (AA 150-505) protein (His tag)Crystallography grade ACVR1B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IB (ACVR1B) (AA 24-126) protein (His tag)Crystallography grade ACVR1B 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Activin A Receptor, Type IB (ACVR1B) (AA 24-505) protein (rho-1D4 tag)Crystallography grade ACVR1B 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))
- 别名
- ALK4/ACVR1B (ACVR1B 产品)
- 别名
- ACVR1B Protein, alk4 Protein, skr2 Protein, alk-4 Protein, xalk4 Protein, actrib Protein, acvrlk4 Protein, DKFZp469A1614 Protein, 6820432J04 Protein, ActR-IB Protein, ActRIB Protein, Acvrlk4 Protein, Alk4 Protein, SKR2 Protein, ACTRIB Protein, ACVRLK4 Protein, ALK4 Protein, Skr2 Protein, axis Protein, taram-a Protein, tarama Protein, wu:fb75f01 Protein, activin A receptor type 1B Protein, Activin receptor type-1B Protein, activin A receptor, type IB Protein, activin A receptor, type 1B Protein, activin A receptor type 1Ba Protein, ACVR1B Protein, acvr1b Protein, acv1b Protein, Acvr1b Protein, acvr1ba Protein
- 背景
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Background: ALK-4 (Activin Receptor-Like Kinase 4) or ACVR1B (Activin A Receptor, type 1B), belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, and TGFB receptor subfamily. ALK-4/ACVR1B acts as a transducer of activin or activin like ligands signals. Activin binds to either ACVR2A or ACVR2B and then forms a complex with ACVR1B. The known type II activin receptors include ActRII and ActRIIB, while the main type I activin receptor in mammalian cells is ALK-4 (ActRIB). In the presence of activin, type II and type I receptors form complexes whereby the type II receptors activate ALK-4 through phosphorylation. The activated ALK-4, in turn, transduces signals downstream by phosphorylation of its effectors, such as Smads, to regulate gene expression and affect cellular phenotype. ALK-4/ACVR1B is an important regulator of vertebrate development, with roles in mesoderm induction, primitive streak formation, gastrulation, dorsoanterior patterning, and left-right axis determination.
Synonym: ACVR1B,Acvrlk4,Alk4
- 分子量
- 38.4 kDa
- NCBI登录号
- NP_954700
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