MALS verified
ROBO1
宿主: 人
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
应用备注
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 97.5 kDa. The protein migrates as kDa under reducing (R) condition due to glycosylation.
Synonyms: ROBO1/DUTT1, Description: ROBO1 is a member of the ROBO immunoglobulin superfamily of proteins, and it plays a crucial role in cell motility and migration during embryogenesis and organogenesis. In addition, evidence showed that ROBO1 might drive migration and invasion in malignant cells, such as glioma and breast cancer, which might play a role in cancer aggressiveness. In contrast, some studies suggested that ROBO1 pathways play a key role in tumors by acting as a tumor suppressor, especially in cell invasion.