Glucagon Receptor Protein (GCGR) (Fc Tag)
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- 抗原 See all Glucagon Receptor (GCGR) 蛋白
- Glucagon Receptor (GCGR)
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This Glucagon Receptor protein is labelled with Fc Tag.
- 原理
- Mouse GCGR / Glucagon receptor Protein, Fc Tag
- 序列
- Ala 27 - Lys 137
- 产品特性
- Mouse GCGR, Fc Tag (GCR-M5254) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Lys 137 (Accession # Q61606-1).
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product GCGR 蛋白
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- 应用备注
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 39.5 kDa. The protein migrates as 50-65 kDa under reducing (R) condition due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- Glucagon Receptor (GCGR)
- 别名
- GCGR / Glucagon receptor (GCGR 产品)
- 别名
- GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein
- 背景
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Synonyms: Glucagon R, GCGR,Glucagon receptor,
Description: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system. - 分子量
- 39.5 kDa
- 途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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