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IL21 Receptor Protein (mFc Tag)

IL21R 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN7092744
发货至: 中国
  • 抗原 See all IL21 Receptor (IL21R) 蛋白
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    蛋白类型
    Recombinant
    宿主
    • 13
    • 8
    • 2
    • 1
    资源
    • 12
    • 5
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This IL21 Receptor protein is labelled with mFc Tag.
    原理
    Recombinant Human IL21R with C-terminal mouse Fc tag
    特异性
    IL21R (Cys20-Glu232) mFc (Pro99-Lys330)
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product IL21R 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
    别名
    IL21R (IL21R 产品)
    别名
    IL21R Protein, il-21ra.a Protein, CD360 Protein, NILR Protein, interleukin 21 receptor Protein, interleukin 21 receptor, tandem duplicate 1 Protein, IL21R Protein, il21r.1 Protein, Il21r Protein
    背景
    Synonymes: CD360, IMD56, NILR
    Description: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
    分子量
    predicted molecular mass of 50.7 kDa after removal of the signal peptide.The apparent molecular mass of IL21R-mFc is 55-70 kDa due to glycosylation.
    UniProt
    Q9HBE5
    途径
    JAK/STAT Signaling
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