IL21 Receptor Protein (AA 20-232) (His tag)
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- 抗原 See all IL21 Receptor (IL21R) 蛋白
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-232
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This IL21 Receptor protein is labelled with His tag.
- 原理
- Human IL-21R Protein
- 序列
- Cys20-Glu232
- 产品特性
- Recombinant Human IL-21R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys20-Glu232.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-21 at 1μg/ml (100μl/well) on the plate. Dose response curve for Human IL-21R, His Tag with the EC50 of 24.3ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product IL21R 蛋白
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Interleukin 21 Receptor (IL21R) (AA 20-236) protein (Fc Tag)
IL21R 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 21 Receptor (IL21R) (AA 41-254) protein (His tag)IL21R 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 21 Receptor (IL21R) protein (His tag)IL21R 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 21 Receptor (IL21R) (AA 20-232) protein (His tag)IL21R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 21 Receptor (IL21R) (AA 1-538) protein (GST tag)IL21R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 21 Receptor (IL21R) (Active) protein (His tag)IL21R 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Interleukin 21 Receptor (IL21R) (AA 254-538) protein (His tag)Crystallography grade IL21R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 21 Receptor (IL21R) (AA 20-237) protein (His tag)Crystallography grade IL21R 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 21 Receptor (IL21R) (AA 259-529) protein (His tag)Crystallography grade IL21R 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Interleukin 21 Receptor (IL21R) (AA 20-538) protein (rho-1D4 tag)Crystallography grade IL21R 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
- 别名
- IL-21R (IL21R 产品)
- 别名
- IL21R Protein, il-21ra.a Protein, CD360 Protein, NILR Protein, interleukin 21 receptor Protein, interleukin 21 receptor, tandem duplicate 1 Protein, IL21R Protein, il21r.1 Protein, Il21r Protein
- 背景
- IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by upregulating RORγt expression and downregulating Foxp3 expression, with increased expression and secretion of IL-17A and IL-22.Microbial translocation and the associated immune activation during HIV-1 infection may lead to high expression levels of the IL-21R activation marker in RM B cells, a feature associated with increased apoptosis and a reduced number of these cells in the circulation.
- 分子量
- 25.65 kDa. Due to glycosylation, the protein migrates to 43-50 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9HBE5
- 途径
- JAK/STAT Signaling
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