FURIN Protein (AA 27-574) (His tag)
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- 抗原 See all FURIN 蛋白
- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
- 蛋白类型
- Recombinant
- 产品特性
- AA 27-574
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FURIN protein is labelled with His tag.
- 原理
- Human Furin / PCSK3 Protein, His Tag
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product FURIN 蛋白
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Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 28-794) protein (GST tag)
FURIN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 108-371) protein (His-IF2DI Tag)FURIN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 1-148) proteinFURIN 宿主: E. coli 宿主: 大肠杆菌（E. Coli） Recombinant SDS
Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 108-794) protein (rho-1D4 tag)Crystallography grade FURIN 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 108-793) protein (rho-1D4 tag)Crystallography grade FURIN 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 20 mM Tris, 150 mM NaCl, pH 9.0
- 储存条件
- -80 °C
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- 抗原
- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
- 别名
- Furin (FURIN 产品)
- 别名
- FURIN Protein, furin Protein, si:dkey-281a24.5 Protein, FUR Protein, LOC100220259 Protein, PACE Protein, spc1 Protein, xfurin Protein, MGC82710 Protein, PCSK3 Protein, SPC1 Protein, 9130404I01Rik Protein, Fur Protein, Pcsk3 Protein, Pace Protein, furin, paired basic amino acid cleaving enzyme Protein, furin (paired basic amino acid cleaving enzyme) a Protein, furin (paired basic amino acid cleaving enzyme) b Protein, furin, paired basic amino acid cleaving enzyme L homeolog Protein, furin (paired basic amino acid cleaving enzyme) Protein, FURIN Protein, furina Protein, furinb Protein, furin Protein, furin.L Protein, Furin Protein
- 背景
- Furin is also known as paired basic Amino acid Cleaving Enzyme (PACE), is an enzyme which belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. The expression of furin in T-cells is required for maintenance of peripheral immune tolerance. Furin cleaves proteins just downstream of a basic amino acid target sequence (canonically, Arg-X-(Arg/Lys) -Arg'). PACE is a calcium-dependent serine endoprotease that can efficiently cleave precursor proteins at their paired basic amino acid processing sites. In addition to processing cellular precursor proteins, furin is also utilized by a number of pathogens. For example, the envelope proteins of viruses such as HIV, influenza and dengue fever viruses must be cleaved by furin or furin-like proteases to become fully functional. PACE also play a role in tumor progression.
- 分子量
- 62.1 kDa
- NCBI登录号
- NM_002569
- 途径
- Notch Signaling, Neurotrophin Signaling Pathway
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