FAP Protein (AA 26-760) (His tag,AVI tag,Biotin)
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- 抗原 See all FAP 蛋白
- FAP (Fibroblast Activation Protein, alpha (FAP))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 26-760
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This FAP protein is labelled with His tag,AVI tag,Biotin.
- 原理
- Biotinylated Cynomolgus FAP Protein, His,Avitag™ (MALS verified)
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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- Discover our top product FAP 蛋白
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Fibroblast Activation Protein, alpha (FAP) (AA 26-760) protein (Fc Tag)
FAP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) protein (His-Avi Tag,Biotin)FAP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) (AA 26-761) protein (His tag)FAP 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Fibroblast Activation Protein, alpha (FAP) (AA 26-760) protein (His tag)FAP 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) protein (His tag)FAP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) (AA 26-760) protein (His-Avi Tag,Biotin)FAP 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Activation Protein, alpha (FAP) (AA 26-760) (Active) protein (Fc Tag)FAP 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Fibroblast Activation Protein, alpha (FAP) (AA 26-760) (Active) protein (His tag)FAP 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Fibroblast Activation Protein, alpha (FAP) (Active) protein (His tag)FAP 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by reducing SDS-PAGE. Active
Fibroblast Activation Protein, alpha (FAP) protein (mFc Tag)FAP 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 说明
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Ready-to-use Avitag™ biotinylated protein:
The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- FAP (Fibroblast Activation Protein, alpha (FAP))
- 别名
- FAP (FAP 产品)
- 别名
- fap-A Protein, gene 13 Protein, FAP Protein, fapa Protein, dppiv Protein, seprase Protein, DPPIV Protein, FAPA Protein, fibroblast activation protein Protein, fibroblast activation protein alpha L homeolog Protein, fibroblast activation protein alpha Protein, fibroblast activation protein, alpha Protein, prolyl endopeptidase FAP Protein, Fap Protein, fap.L Protein, FAP Protein, fap Protein, LOC100547273 Protein
- 背景
- FAP (also known as seprase) is a Type II transmembrane serine protease. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences. Degrade also gelatin, heat-denatured type I collagen. Also has dipeptidyl peptidase activity, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro. The plasma membrane form, in association with either DPP4, PLAUR or integrins, is involved in the pericellular proteolysis of the extracellular matrix (ECM), and hence promotes cell adhesion, migration and invasion through the ECM. Promotes glioma cell invasion through the brain parenchyma by degrading the proteoglycan brevican. Acts as a tumor suppressor in melanocytic cells through regulation of cell proliferation and survival in a serine protease activity-independent manner.
- 分子量
- 92.6 kDa
- NCBI登录号
- NP_004451
- 途径
- Tube Formation
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