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FAP Protein (AA 26-760) (Fc Tag)

FAP 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
产品编号 ABIN7013469
发货至: 中国
  • 抗原 See all FAP 蛋白
    FAP (Fibroblast Activation Protein, alpha (FAP))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 26-760
    宿主
    • 17
    • 10
    • 3
    • 3
    资源
    • 17
    • 6
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This FAP protein is labelled with Fc Tag.
    产品特性
    Human FAP Protein, Fc Tag (active enzyme)
    纯度
    >90 % as determined by SDS-PAGE.
    内毒素水平
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product FAP 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
  • 抗原
    FAP (Fibroblast Activation Protein, alpha (FAP))
    别名
    FAP (FAP 产品)
    别名
    fap-A Protein, gene 13 Protein, FAP Protein, fapa Protein, dppiv Protein, seprase Protein, DPPIV Protein, FAPA Protein, fibroblast activation protein Protein, fibroblast activation protein alpha L homeolog Protein, fibroblast activation protein alpha Protein, fibroblast activation protein, alpha Protein, prolyl endopeptidase FAP Protein, Fap Protein, fap.L Protein, FAP Protein, fap Protein, LOC100547273 Protein
    背景
    FAP (also known as seprase) is a Type II transmembrane serine protease. Both plasma membrane and soluble forms exhibit post-proline cleaving endopeptidase activity, with a marked preference for Ala/Ser-Gly-Pro-Ser/Asn/Ala consensus sequences. Degrade also gelatin, heat-denatured type I collagen. Also has dipeptidyl peptidase activity, with a preference for Ala-Pro, Ile-Pro, Gly-Pro, Arg-Pro and Pro-Pro. The plasma membrane form, in association with either DPP4, PLAUR or integrins, is involved in the pericellular proteolysis of the extracellular matrix (ECM), and hence promotes cell adhesion, migration and invasion through the ECM. Promotes glioma cell invasion through the brain parenchyma by degrading the proteoglycan brevican. Acts as a tumor suppressor in melanocytic cells through regulation of cell proliferation and survival in a serine protease activity-independent manner.
    分子量
    111.5 kDa
    途径
    Tube Formation
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