JAK1 Protein (AA 561-852) (His tag)
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- 抗原 See all JAK1 蛋白
- JAK1 (Janus Kinase 1 (JAK1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 561-852
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宿主
- 人
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资源
- Insect Cells
- 标记
- This JAK1 protein is labelled with His tag.
- 产品特性
- Human JAK1 Protein, His Tag
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product JAK1 蛋白
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Janus Kinase 1 (JAK1) (AA 850-1154) (Active) protein (GST tag)
JAK1 宿主: 人 宿主: Insect cells (Sf21) Recombinant SDS, Func Active
Janus Kinase 1 (JAK1) (AA 221-320) protein (GST tag)JAK1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Janus Kinase 1 (JAK1) (AA 1-1154) protein (Strep Tag)Crystallography grade JAK1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Janus Kinase 1 (JAK1) (AA 1-1153) protein (Strep Tag)Crystallography grade JAK1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Janus Kinase 1 (JAK1) proteinJAK1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
Janus Kinase 1 (JAK1) protein (Myc-DYKDDDDK Tag)JAK1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 50 mM Tris, 500 mM NaCl, 2 mM TCEP, pH 8.0
- 储存条件
- -80 °C
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- 抗原
- JAK1 (Janus Kinase 1 (JAK1))
- 别名
- JAK1 (JAK1 产品)
- 别名
- JAK1A Protein, JAK1B Protein, JTK3 Protein, AA960307 Protein, C130039L05Rik Protein, wu:fb93e10 Protein, jak1 Protein, Janus kinase 1 Protein, tyrosine-protein kinase JAK1 Protein, JAK1 Protein, Jak1 Protein, jak1 Protein, LOC100286690 Protein
- 背景
- JAK1 is a human tyrosine kinase protein essential for signaling for certain type I and type II cytokines. It interacts with the common gamma chain (γc) of type I cytokine receptors, to elicit signals from the IL-2 receptor family (e.g. IL-2R, IL-7R, IL-9R and IL-15R), the IL-4 receptor family (e.g. IL-4R and IL-13R), the gp130 receptor family (e.g. IL-6R, IL-11R, LIF-R, OSM-R, cardiotrophin-1 receptor (CT-1R), ciliary neurotrophic factor receptor (CNTF-R), neurotrophin-1 receptor (NNT-1R) and Leptin-R). Jak1 plays a critical role in initiating responses to multiple major cytokine receptor families. Expression of JAK1 in cancer cells enables individual cells to contract, potentially allowing them to escape their tumor and metastasize to other parts of the body
- 分子量
- 35.7 kDa
- 途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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