SARS-CoV-2 Spike Protein (His tag)
Quick Overview for SARS-CoV-2 Spike Protein (His tag) (ABIN7013277)
抗原
See all SARS-CoV-2 Spike 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This SARS-CoV-2 Spike protein is labelled with His tag.
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序列
- AA 16-1213
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特异性
- SARS-CoV-2 S protein (F817P, A892P, A899P, A942P, K986P, V987P), His Tag (MALS verified)
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产品特性
- SARS-CoV-2 S protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein.
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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应用备注
- MALS verified
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS
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储存条件
- -20 °C
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- SARS-CoV-2 Spike
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别名
- SARS-CoV-2 S protein
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物质类
- Viral Protein
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背景
- It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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分子量
- 138.2 kDa
抗原
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