K-RAS Protein (AA 1-169) (His tag)
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- 抗原 See all K-RAS (KRAS) 蛋白
- K-RAS (KRAS) (GTPase Kras (KRAS))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-169
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宿主
- 人
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资源
- Insect Cells
- 标记
- This K-RAS protein is labelled with His tag.
- 产品特性
- Human KRAS Protein, His Tag
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product KRAS 蛋白
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GTPase Kras (KRAS) protein (His tag)
KRAS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by reducing SDS-PAGE.
GTPase Kras (KRAS) (AA 1-185) protein (His tag)KRAS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
GTPase Kras (KRAS) (AA 1-186) protein (His tag)KRAS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
GTPase Kras (KRAS) (AA 1-189) protein (GST tag)KRAS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
GTPase Kras (KRAS) (AA 1-188) protein (GST tag)KRAS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
GTPase Kras (KRAS) (AA 16-125) protein (GST tag)KRAS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 50 mM Tris, 0.5 M NaCl, pH 7.5
- 储存条件
- -20 °C
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- 抗原
- K-RAS (KRAS) (GTPase Kras (KRAS))
- 别名
- KRAS (KRAS 产品)
- 别名
- wu:fa04e08 Protein, wu:fc14b12 Protein, wu:fc23g10 Protein, wu:fj89d12 Protein, zgc:85725 Protein, Kras2 Protein, c-Ki-ras Protein, p21 Protein, C-K-RAS Protein, CFC2 Protein, K-RAS2A Protein, K-RAS2B Protein, K-RAS4A Protein, K-RAS4B Protein, KI-RAS Protein, KRAS1 Protein, KRAS2 Protein, NS Protein, NS3 Protein, RASK2 Protein, AI929937 Protein, K-ras Protein, Ki-ras Protein, Kras-2 Protein, p21B Protein, ras Protein, k-ras Protein, kras Protein, kras-a Protein, kras-b Protein, rask2 Protein, K-RAS Protein, p21ras Protein, KRAS proto-oncogene, GTPase Protein, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog Protein, Kirsten rat sarcoma viral oncogene homolog Protein, semicolonial-7 Protein, Ras family protein Protein, GTPase KRas Protein, Kirsten rat sarcoma viral oncogene homolog S homeolog Protein, KRAS Protein, kras Protein, Kras Protein, smco-7 Protein, PGTG_03066 Protein, Tsp_02666 Protein, Tsp_01642 Protein, rask Protein, kras.S Protein
- 物质类
- Viral Protein
- 背景
- KRAS (Kirsten rat sarcoma 2 viral oncogene homolog) gene is a proto-oncogene that encodes a small GTPase transductor protein called KRAS. KRAS is also known as Ki-Ras, c-K-ras and c-Ki-ras. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation, promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner. RAS is one of the most frequently mutated oncogenes in human cancer but the frequency and distribution of RAS gene mutations are not uniform. In details, mutation of glycine 12 (G12) causes RAS activation by interfering with GAP binding and GAP-stimulated GTP hydrolysis. The reference shows the pathway may as a potential therapy targets.
- 分子量
- 21.3 kDa
- NCBI登录号
- NP_004976
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