MARCO Protein (AA 79-520) (His tag)
MARCO
宿主: 人
宿主: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
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- 抗原 See all MARCO 蛋白
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
- 蛋白类型
- Recombinant
- 产品特性
- AA 79-520
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MARCO protein is labelled with His tag.
- 原理
- Human MARCO Protein, His Tag
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MARCO 蛋白
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Macrophage Receptor with Collagenous Structure (MARCO) (AA 70-518) protein (His tag)
MARCO 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Macrophage Receptor with Collagenous Structure (MARCO) (AA 405-520) protein (His tag)MARCO 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
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- 抗原
- MARCO (Macrophage Receptor with Collagenous Structure (MARCO))
- 别名
- MARCO (MARCO 产品)
- 别名
- AI323439 Protein, Ly112 Protein, Scara2 Protein, SCARA2 Protein, macrophage receptor with collagenous structure Protein, MARCO Protein, Marco Protein
- 背景
- MARCO is also known as Scavenger receptor class A member 2 and SCARA2. Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria. Also plays a role in binding of unopsonized particles by alveolar macrophages. Binds to the secretoglobin SCGB3A2. MARCO ligation promotes the production of inflammatory mediators by macrophages. MARCO mediated internalization of some ligands prevents their activation of cell surface TLR4 but enables their activation of intracellular TLR3. MARCO contributes to the clearance of apoptotic cells and inhaled bacteria, mast cell mediated silicosis, and the amelioration of allergen or ozone induced lung inflammation. It is required for the organization of the splenic marginal zone and the interaction of splenic macrophages and B cells.
- 分子量
- 45.9 kDa
- 途径
- Activation of Innate immune Response
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